Seven new sesquiterpene lactone glycosides (1-7) were isolated from the H2O-soluble fraction from the MeOH extract of the roots of Ferula varia. Their structures were elucidated by extensive spectroscopic analyses. The absolute configurations of compounds 1 and 2 were determined by modified Mosher's method.

in this study, the ability of generalized additive model (gam) for mapping potential distribution of ferula ovina boiss, and the description of species response curves to environmental variables were examined in fereidonshar region with area of 1000 square kilometers located in west of isfahan province. the presence and absence data of the species were collected from 278 sites (including 138 pr...

objective: alpha-glucosidase, as a carbohydratase catalyses the liberation of alpha-glucose from the nonreducing end of some carbohydrates from foods in digestive tract.  consequently, retard absorption of glucose by the inhibition of carbohydrate hydrolyzing enzymes is one of the therapeutic approaches to decrease the postprandial hyperglycemia. recently, a great deal of attention has been pai...

Objective: Alpha-glucosidase, as a carbohydratase catalyses the liberation of alpha-glucose from the nonreducing end of some carbohydrates from foods in digestive tract.  Consequently, retard absorption of glucose by the inhibition of carbohydrate hydrolyzing enzymes is one of the therapeutic approaches to decrease the postprandial hyperglycemia. Recently, a great deal of attention has been pai...

From the dichloromethane extract of aerial parts of Ferula vesceritensis (Apiaceae), 11 sesquiterpene derivatives were isolated. Among them five were compounds designated as 10-hydroxylancerodiol-6-anisate, 2,10-diacetyl-8-hydroxyferutriol-6-anisate, 10-hydroxylancerodiol-6-benzoate, vesceritenone and epoxy-vesceritenol. The six known compounds were identified as feselol, farnesiferol A, lapido...

ferula gummosa boiss is a good source of biologically active compounds such as monoterpene and sesquiterpene derivatives. there are also several reports on antioxidant effects of these compounds. the aim of this study was to investigate the effect of daily administration of f. gummosa root hydro-alcoholic extract on serum oxidant-antioxidant status. twenty four wistar rats were randomly divided...