This study was undertaken to determine the mechanisms mediating changes in fetal heart rate variability (FHRV) during and after exposure to asphyxia in the premature fetus. Preterm fetal sheep at 0.6 of gestation (91 +/- 1 days, term is 147 days) were exposed to either sham occlusion (n = 10) or to complete umbilical cord occlusion for either 20 (n = 7) or 30 min (n = 10). Cord occlusion led to...

Renal impairment is common in preterm infants, often after exposure to hypoxia/asphyxia or other circulatory disturbances. We examined the hypothesis that this association is mediated by reduced renal blood flow (RBF), using a model of asphyxia induced by complete umbilical cord occlusion for 25 min (n = 13) or sham occlusion (n = 6) in chronically instrumented preterm fetal sheep (104 days, te...

Objective: To analyze maternal and perinatal outcomes in pregnancies complicated by pre-gestational gestational diabetes.
 Methods: This is an analytical observational study with a cross-sectional design. We examined 57 women, 39 of diabetes mellitus (PGDM) 19 had (GDM). The data were analyzed using the chi-square Fisher’s exact test.
 Results: There no deaths either group. Pre-eclamp...

BACKGROUND Respiratory distress syndrome (RDS) is a common critical disease in term neonates, but reasons for the occurrence of RDS remains unclear. AIMS This study aimed to investigate the cause of RDS in full-term neonates by a retrospective case-control study. STUDY DESIGN Case-control study. METHODS Among the patients admitted to Bayi Children's Hospital between January 2008 and Decem...

• Two principal mechanisms have been proposed to explain closure of the ductus arteriosus. Bareroft et al.2 thought that functional closure of this vessel occurred shortly after clamping the umbilical cord and that the stimulus for closure was neurogenic. Kennedy and Clark' failed to find a neurogenie mechanism and suggested that closure was related to increased oxygenation of the bJood followi...

The details of the deliveries of 10 infants whose cords were clamped before the onset of respiration and within one minute of delivery of the chin but whose residual placental volumes were unexpectedly low are compared with 20 control infants whose cords were clamped under similar conditions but who had the expected residual placental volumes. The only statistically significant difference betwe...

Intrauterine inflammation/infection has been associated with prenatal mortality and morbidity. However, few studies have been performed to investigate how the fetus responds to intrauterine inflammation/infection in utero. In the present study, fetal plasma prostaglandin (PG) F(2alpha) and cortisol responses to high-dose fetal endotoxin administration were evaluated in late gestation goats (n=8...

A more common problem associated with epidural and spinal anesthesia i s maternal hypotension. This i s due to sympathetic blockade, affecting the arterial äs well äs the venous circulation. Arterial relaxation wi l l lower the peripheral resistance, whi le venous relaxation tends to produce peripheral pooling of blood, and reduction in cardiac Output. The resulting hypotension may diminish the...