Fetal growth restriction can affect health outcomes in postnatal life. This study tested the hypothesis that response to an inflammatory pulmonary insult is altered pediatric fetal restricted rats. Using a low-protein diet during gestation and life, growth-restricted male female rats healthy control were exposed via intratracheal instillation of heat-killed bacteria. After 6 h, animal lungs exa...

Background: Extraction of Fetal ECG signal from non-invasive abdominal ECG signal is an important clinical application. Fetal ECG signal provides significant and valuable information about the fetal heart growth and health condition. Objective: Abdominal signals are usually corrupted by high amplitude maternal ECG signals and often found superimposed with the Fetal ECG signal. Suppression of ma...

†Fetal Therapy Program, Albert Einstein Hospital, São Paulo, Brazil; ‡Office of the Dean and Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA; §Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; ¶Department of Obstetrics and Gynecology, University ...

Determining the optimal timing for induction of labor is critical in minimizing the risks to maternal and fetal health. While data are available to guide us in some clinical situations, such as hypertension and diabetes, many gaps in knowledge still exist in others, including cholestasis of pregnancy, fetal anomalies, and placental abruption. This review of the currently available literature as...

The fetal programming and developmental origins of disease models suggest that experiences that occur before birth can have consequences for physical and mental health that persist across the lifespan. Development is more rapid during the prenatal period as compared to any other stage of life. This introductory article considers evidence that fetal exposure to stress and stress hormones influen...

The obesity epidemic is a problem of global importance with a profound impact on maternal-fetal health. Maternal overweight and obesity causes pregnancy complications such as gestational diabetes, hypertension and preeclampsia and affects fetal growth. Maternal obesity offers an altered genetic, hormonal and biochemical environment for the developing fetus/embryo and influences fetal growth and...

Advancements in maternal–fetal interventions have allowed for direct fetal access, shifting the focus of from maternal health to a on sole fetal/neonatal benefit. Given that access fetus can only be obtained through mother, there are ethical considerations important consider when counseling dyad. The goals range improved survival decreased long-term morbidities and quality life. However, improv...