OBJECTIVE Pregnancy in type 1 diabetic women remains a high-risk situation for both mother and child. In this study, we investigated long-term effects on body composition, prevalence of overweight, and insulin resistance in children of type 1 diabetic women who had had adequate glycemic control during pregnancy (mean A1C 6.2%), and we related their outcome to perinatal factors, including macros...

Fetuses of mothers with gestational diabetes mellitus are at increased risk to develop perinatal complications mainly due to macrosomia. However, in view of the marked heterogeneity of this disease, it seems difficult to set guidelines for diagnosis and treatment. This complicates the choice of assigning patients either to diet or to insulin therapy. Also of concern is how much benefit could be...

conclusions in this study, hepatitis b had a cause effect on lga and fetal macrosomia. among the other considered adverse pregnancy outcomes; it didn’t have any significant effect. context hepatitis is a term used to describe any type of hepatitis inflammation. screening for the virus antigen during pregnancy is mandatory in some parts of the world and is recommended in others. so that, most wo...

OBJECTIVE To determine a precise estimate for the contribution of maternal obesity to macrosomia. DATA SOURCES The search strategy included database searches in 2011 of PubMed, Medline (In-Process & Other Non-Indexed Citations and Ovid Medline, 1950-2011), and EMBASE Classic + EMBASE. Appropriate search terms were used for each database. Reference lists of retrieved articles and review articl...

In 2011, 1 in 3 women who gave birth in the United States did so by cesarean delivery. Cesarean birth can be lifesaving for the fetus, the mother, or both in certain cases. However, the rapid increase in cesarean birth rates from 1996 through 2011 without clear evidence of concomitant decreases in maternal or neonatal morbidity or mortality raises significant concern that cesarean delivery is o...

OBJECTIVES This study aimed to ascertain the frequency of polyhydramnios in singleton pregnancies, to determine the associated risk factors, and assess the adverse maternal and perinatal outcomes. METHODS A retrospective cohort study of all singleton pregnancies complicated with polyhydramnios after 28 weeks of gestation was carried out in Nizwa Hospital's Obstetrics & Gynecology Department, ...

BACKGROUND Survivin (a member of the inhibitors of apoptosis family) is important for fetal development, placental survival and differentiation. Intrauterine growth restriction (IUGR) and fetal macrosomia, due to maternal diabetes mellitus (DM) are associated with excessive and decreased feto-placental apoptosis, respectively. The aim was to study survivin concentrations in cord blood at term i...