Purpose. Angiosome-guided revascularization is an approach that improves wound healing but requires a surgeon to determine which angiosomes are ischemic. This process can be more difficult than anticipated because diabetic foot (DF) wounds vary greatly in quantity, morphology, and topography. This paper explores to what extent the heterogeneous presentation of DF wounds impedes development of a...

background: the process of wound healing involves integrated events including inflammation, granulation tissue formation, matrix deposition and remodeling. growth factors play a key role in the process. among them transforming growth factor-ß1 (tgf-ß1) is known to accelerate tissue repair by promoting the synthesis and deposition of extracellular matrix proteins. however, persistence or overact...

UNLABELLED  Introduction. Treating difficult-to-heal wounds with complexities, including those with exposed tendon/bone or infection, is a challenge that regularly confronts practitioners in a variety of clinical environments. The purpose of this study was to review the effectiveness of an acellular fetal bovine dermal repair scaffold (PriMatrix Dermal Repair Scaffold, TEI Biosciences, In...

The medical response to mass casualty terrorist bombings (MCTB) has received extensive treatment in the trauma and emergency medicine literature over the past 25 years. An effective medical response must consider four fundamental aspects: (1) the objective of the response, (2) the typical injury pattern, (3) triage, and (4) the delivery of care. This report discusses the key components of each ...

Opposing authors provide succinct, authoritative discussions of controversial issues in emergency medicine. Authors are provided the opportunity to review and comment on opposing presentations. Each topic is accompanied by an Editor’s Note that summarizes important concepts. Participation as an authoritative discussant is by invitation only, but suggestions for topics and potential authors can ...

Previous measurements of the lateral electric fields near skin wounds in guinea pigs have detected DC fields between 100-200 mV/mm near the edge of the wound. We have studied the translocation response of motile primary human keratinocytes migrating on a collagen substrate while exposed to similar physiological DC electric fields. We find that keratinocytes migrate randomly on collagen in field...

From the moment of birth to the final disposal of the dead body the skin is the recipient of care. Throughout life every traumatic encounter with the environment results in the need to look at and touch the largest organ of the body. Looking and touching is low technology requiring an evidence base and a curriculum developed from Dermatology, but utilizable by all. This journal has frequently p...

OBJECTIVES The differences between pediatric (< or = 17 years of age) and adult clinical field encounters were analyzed from four deployments of Disaster Medical Assistance Teams (DMATs). METHODS A retrospective cohort review of all patients who presented to DMAT field clinics during two hurricanes, one earthquake, and one flood was conducted. Descriptive statistics were used to analyze: (1) ...

Physical and psychosocial functioning following motor vehicle trauma The relationship between posttraumatic stress disorder and trauma cognitions Infections and treatment of wounds in survivors of the 2004 Tsunami in Thailand Field hospital analgesia The evolution of pain management in the critically ill trauma patient What is the ideal pre-hospital analgesic? Continuous infusion of local...