In this case study we illustrate the high complexity of a rather simple inter-agency e-government service: change of address in Switzerland. This enables us to identify typical sources and dimensions of complexity for inter-agency services in countries with decentralised competencies among government agencies. From the resulting picture we draw conclusions on how to deal with complexity – and h...

The case for an increase in the role of insurance provision in the fight against poverty and vulnerability is well-established. This paper asks how it can be more effectively delivered to the poor, and what its role should be relative to other microfinance programmes, safety nets and informal insurance systems. It focuses on the various interactions, including how insurance may crowd out credit...

This article describes a system (Framework for Intervention) for dealing with behaviour problems . Problems in the current system are discussed. There is a description of the Framework and the trial of the procedures that took place in 1997. The current programme in Birmingham is outlined. The article argues that the system is both unique and possibly the only systematic hope in the fight to re...

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With EMA approval in December 2015, and US FDA approval in October 2015 of an oncolytic herpesvirus for the treatment of nonresectable melanoma, we now have a novel class of anticancer agents to add to our ever-promising arsenal of cancer (immuno-) therapeutics. Talimogen laherparapvec (T-VEC) therapy involves direct, intratumoral injection of a herpes simplex type 1 (HSV-1) virus which has bee...

Each year, twice as many people die in Europe from hospital acquired infections than from road accidents. These infectious diseases have developed antibiotic resistance and spread despite the best efforts of staff, mainly through textiles like bed linen. But the technology developed by a European research project helps fight back against the so-called superbugs, by using a revolutionary nanotec...