Abstract Green analytical chemistry is an important area of chemical sciences. So, developing competent eco-friendly tools a big challenge. This study devotes two chromatographic techniques for the simultaneous determination binary formulated mixture oxytetracycline HCl (OXY) and flunixin meglumine (FLU), their impurities tetracycline (TRC) 2-chloronicotinic acid (CNA), respectively. Primarily,...