OBJECTIVE To evaluate the malignancy rate of focal thyroid incidentaloma (fTI) in a population of patients undergoing a 18F-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) for a non-thyroid purpose. DESIGN We conducted a prospective cohort study from January 2013 to November 2014. All consecutive patients referred for a FDG PET-CT were prospectively screened. ...

OBJECTIVES To evaluate the positive predictive value of a thyroid nodule being malignant when categorized as atypical, and to determine the prognostic implications of specific cytopathological features. DESIGN Retrospective review of consecutive patients undergoing thyroid surgery following fine-needle aspiration biopsy (FNAB) of thyroid nodules. SETTING Academic teaching hospital in Toront...

BACKGROUND Accurate preoperative assessment of thyroid nodules with fine-needle aspiration biopsy (FNAB) continues to be a challenge, often resulting in unnecessary diagnostic surgical intervention. The detection of several novel gene mutations in differentiated thyroid cancer (DTC) over the last decade has led to the diagnostic use of these oncogenic alterations to improve FNAB sensitivity and...

BACKGROUND Breast metaplastic squamous cell carcinoma (SCC) is a rare primary breast carcinoma, and overexpression of HER2 in this carcinoma is extremely uncommon. CASE REPORT We presented a case of a 48-year-old Asian female with breast metaplastic SCC. Fine needle aspiration biopsy (FNAB) and core needle biopsy (CNB) of the lesion were taken prior to surgical resection. FNAB smears demonstrat...

Objective: This article concerns evaluation of the sensitivity, specificity and accuracy of FNAB for pre-surgical diagnosis of benign and malignant lesions of major and minor salivary glands of patients treated in the Department of Head and Neck Surgery of Erasto Gartner Hospital. Methods: This retrospective study analyzed medical records from January 2006 to December 2011 from patients with sa...

OBJECTIVE To show the benefits of fine-needle aspiration biopsy (FNAB) in managing thyroid nodules. METHODS As a retrospective study, reports of 888 FNABs of the thyroid performed during a period of 11 years (1996-2007) at Tehran University of Medical Sciences, Sina Hospital and Endocrine Clinic, Tehran, Iran were reviewed. Histological diagnoses were available for 182 cases, and we compared ...

Fine needle aspiration biopsy (FNAB) of the thyroid is limited in distinguishing hyperplastic nodular goiter from true follicular neoplasm and in separating follicular adenoma from follicular carcinoma. The present study was done to evaluate if the morphologic and morphometric investigations and silver staining of nucleolar organizer regions (NORs), either alone or in association would help to ...

similar rigidity but a different biology (chronic pancreati-tis vs pancreatic cancer). 4,7 At present it can be useful in cases with negative FNAB or as a guide for directing FNAB into zones that have a greater probability of malignancy (hard) and avoid necrotic tissue (soft). It cannot yet replace EUS-guided FNAB. Further studies are required that evaluate and determine the specific role of EU...

OBJECTIVE The aim of this study was to determine the efficacy of the use of an ultrasound-guided fine-needle aspiration biopsy (US-FNAB) to diagnose thyroid nodules smaller than 5 mm in the maximum diameter and to evaluate pathological findings of small thyroid malignancies. MATERIALS AND METHODS From May 2007 to April 2008, we evaluated the findings of US-FNABs of small thyroid nodules less ...