Group G streptococcus (GGS) is a human pathogen of emerging clinical significance. It causes skin and soft tissue infections, occasionally resulting in life-threatening conditions such as sepsis and necrotizing fasciitis. We recently identified FOG, a novel surface protein of GGS with fibrinogen binding and immune evasion properties. Here we investigated the role of FOG in streptococcal primary...

Movement disorders are 1 of the long-term neurological complications that can occur after hypoxic-ischemic brain injury (HIBI). However, freezing of gait (FOG) after HIBI is rare. The aim of this study was to examine the brain metabolism of patients with FOG after HIBI using F-18 fluoro-2-deoxy-D-glucose positron emission tomography (F-18 FDG PET).We consecutively enrolled 11 patients with FOG ...

Internet of Things is the future of the Internet. It encircles a wide scope. There are currently billions of devices connected to the Internet and this trend is expecting to grow exponentially. Cisco predicts there are at present 20 billion connected devices. These devices, along with their varied data types, transmission rates and communication protocols connect to the Internet seamlessly. The...

Limited visibility due to fog poses a significant danger to travelers. Accurate fog forecasts provide travelers with ample time to make preparations for low visibility conditions. Previous to this study, the Miami’s NWS Weather Forecast Office used a combination of factors to forecast fog, mainly moisture and wind speeds derived from forecast and observed soundings. However, a quantitative appr...

The critical regulator of hematopoiesis GATA-1 recruits diverse coregulators to chromatin, which mediate transcriptional activation and repression. These coregulators include the cell-type-specific multi-zinc finger protein Friend of GATA-1 (FOG-1), the histone acetyltransferase CREB binding protein (CBP), and the key component of the Mediator complex Med1. While FOG-1 is an established GATA-1 ...

Freezing of gait (FOG) is common in advanced Parkinson's disease (PD), is resistant to treatment and negatively impacts quality of life. In this study an ambulatory FOG monitor was validated in 11 PD patients. The vertical linear acceleration of the left shank was acquired using an ankle-mounted sensor array that transmitted data wirelessly to a pocket PC at a rate of 100 Hz. Power analysis sho...

During gastrulation in Drosophila, ventral cells change shape, undergoing synchronous apical constriction, to create the ventral furrow (VF). This process is affected in mutant embryos lacking zygotic function of the folded gastrulation (fog) gene, which encodes a putative secreted protein. Fog is an essential autocrine signal that induces cytoskeletal changes in invaginating VF cells. Here we ...

The heavy-fog statistics for 256 first-order weather stations were utilized to update analyses of the geographic distribution of f o g within the conterminous United States. The survey shows that heavy fog (visibility one-fourth mile or less) occurs more than 20 days a year at approximately 50 percent of the first-order weather stations (of which 229 are air terminals) and that the mean heavy-f...

Freezing of gait (FoG) is a transient inability to initiate or maintain stepping that often accompanies advanced Parkinson's disease (PD) and significantly impairs mobility. The current study uses a multimodal neuroimaging approach to assess differences in the functional and structural locomotor neural network in PD patients with and without FoG and relates these findings to measures of FoG sev...

9 Across most Mediterranean-type climate regions, seasonal drought desiccates plants, facilitating ignition 10 and the spread of wildfires. Along the California coast, summertime fog has the potential to ameliorate 11 drought conditions and thus reduce plant flammability during a critical time of elevated fire risk. This 12 study investigated the uptake of dry season fog and how it affects live...