including ovarian follicular development and luteinization via altering anti-müllerian hormone (AMH) signalling, follicle-stimulating hormone sensitivity and progesterone production in human granulosa cells1. It also affects glucose homeostasis through manifold roles. The potential influences of vitamin D on glucose homeostasis include the presence of specific vitamin D receptor (VDR) in pancre...

background: estradiol (e2) is required for follicular development and play an important role in embryo implantation. objective: the aim of this study was to assess the impact of serum e2 levels on the day of hcg administration in ivf-icsi patients who are performed controlled ovarian hyperstimulation (coh). materials and methods: a total of 203 women who were undergone one time ivf cyclus were ...

The effects of profound suppression of circulating luteinizing hormone (LH) during the follicular phase of in-vitro fertilization cycles were explored in normal women during treatment with a gonadotrophin-releasing hormone analogue and exogenous purified follicle stimulating hormone. Ovarian responses to treatment and the capacity of supernumerary embryos to undergo blastocyst formation were ex...

A cellular receptor for erythroid differentiation factor (EDF) was demonstrated by incubation of 125I-labeled EDF with rat follicular granulosa cell cultures. The specific binding of labeled EDF to the cells showed saturation; Scatchard analysis of binding data indicated a single class of receptors having Kd = 3.4 x 10(-10) M. A large excess of unlabeled EDF reduced labeled EDF binding almost c...

The seed cycling/seed rotation diet is a new trend that claims to be effective for female menstrual dysfunctions such as irregular menstruation, cramps, infertility, menopausal symptoms (hot flashes, fatigue, etc.), and PCOS. higher prevalence of hormonal imbalance in women contributing factor all these dysfunctions. major hormones control menstruation females include progesterone, estrogen, lu...

The actions, localization, and regulation of activin in the human ovary are unknown. Therefore, the aims of this study were (a) to define the effects of recombinant activin-A and its structural homologue, inhibin-A, on mitogenesis and steroidogenesis (progesterone secretion and aromatase activity) in human preovulatory follicular cells; (b) to localize the activin-A dimer in the human ovary by ...

Ovarian follicular cysts are anovulatory follicular structures that lead to infertility. Hormones play key roles in the formation and persistence of cysts. Inhibins are heterodimeric gonadal glycoprotein hormones that belong to the transforming growth factor-β superfamily. These hormones suppress the secretion of follicle-stimulating hormone. In this report, partial fragment of inhibin-α (INHA)...

Thyroid stimulating hormone (TSH)-associated follicular hypertrophy and hyperplasia as a mechanism of thyroid carcinogenesis in mice and rats G. A mechanistic relationship between thyroid follicular cell tumours and hepatocellular neoplasms in rodents Human renal-cell carcinoma—epidemiological and mechanistic aspects A. Mellemgaard Human renal carcinoma—pathogenesis and biology J.B. Beckwith a ...

background: asparagus is a plant with high nutritional, pharmaceutical, and industrial values. objective: the present study aimed to evaluate the effect of aqueous extract of asparagus roots on the hypothalamic-pituitary-gonadal axis hormones and oogenesis in female rats. materials and methods: in this experimental study, 40 adult female wistar rats were divided into five groups, which consist ...