نتایج جستجو برای: formulation excipients
تعداد نتایج: 112735 فیلتر نتایج به سال:
Binders are important ingredients of solid oral dosage formulations (SODFs). The structure and function of binders play an important role in dosages’ shape and size, delivery, and stability of drug products. The stability of active ingredients depends on external factors, e.g. exposure to heat, oxygen and humidity but also on internal factors, e.g. the impurities such as peroxides, aldehydes, h...
The impact of melt extrusion (HME) and spray drying (SD) on mechanical properties of hypromellose acetate succinate (HPMCAS), copovidone, and their formulated blends was studied and compared with that of reference excipients. Tensile strength (TS), compression pressure (CP), elastic modulus (E), and dynamic hardness (Hd ) were determined along with Hiestand indices using compacts prepared at a ...
The use of lipid-based dosage forms for enhancement of drug absorption or delivery has drawn considerable interest from pharmaceutical scientists. The unique characteristics of these dosage forms, however, present significant challenges to pharmaceutical industry and regulatory agencies in many ways. For example, safety assessment is necessary when the use of a new lipid excipient is considered...
Nebivolol hydrochloride is a poorly water soluble drug falls under class II biopharmaceutical classification system, which is β1 receptor antagonist that leads to vasodilatation, decreased peripheral vascular resistance, lowers blood pressure and heart rate. The rate of its oral absorption is often controlled by dissolution rate in the gastro intestinal tract. The aim of the present investigati...
Objective: During drug preformulation studies, thermal analysis and spectroscopic techniques are used to detect physical or chemical incompatibilities between the active compound excipients in formulation, demonstrate safety and/or efficacy of final product. It has revolutionized erectile dysfunction with development a selective cyclic guanosine monophosphate-specific PDE-5 inhibitors. Tadalafi...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید