The oxidative stress causes many diseases in human, therefore antioxidants have a specialposition in the medicinal chemistry. Tyrosol is an important antioxidant with a plenty ofbiological properties. There are many strategies such as clustering single drug units in orderto develop new drugs. The cluster effect can increase drug effects relative to single drug unit.Calixtyrosol is the novel clu...

The oxidative stress causes many diseases in human, therefore antioxidants have a specialposition in the medicinal chemistry. Tyrosol is an important antioxidant with a plenty ofbiological properties. There are many strategies such as clustering single drug units in orderto develop new drugs. The cluster effect can increase drug effects relative to single drug unit.Calixtyrosol is the novel clu...

the oxidative stress causes many diseases in human, therefore antioxidants have a specialposition in the medicinal chemistry. tyrosol is an important antioxidant with a plenty ofbiological properties. there are many strategies such as clustering single drug units in orderto develop new drugs. the cluster effect can increase drug effects relative to single drug unit.calixtyrosol is the novel clu...

Haemorrhagic shock is associated with hyperproduction of free radicals. Hence ascorbic acid (AA), a free radical scavenger, may be of benefit in such cases. We investigated in Wistar rats the role of free radicals in causing cardiovascular depression and the protective role of ascorbic acid, if any, in acute haemorrhage. The rats were catheterized for recording hemodynamic parameters. Acute hae...

Glucose-6-phosphate dehydrogenase (G6PD) deficient subjects are vulnerable to oxidative stress. Quercetin, a flavonoids, has been employed as a potent oxygen-free radical scavenger in order to assess the protective effects of quercetin against H2O2-induced oxidative damage in G6PD-deficient and normal human erythrocytes. Erythrocytes of G6PD-deficient (n = 10) and normal (n = 10) subjects were ...

Antioxidant potential of leaves of three different species of Annona was studied by using different in vitro models eg., 1,1-diphenyl-2-picryl hydrazyl (DPPH), 2,2-azinobis-(3-ethylbenzothizoline-6-sulphonate) (ABTS), nitric oxide, superoxide, hydroxy radical and lipid peroxidation. The ethanolic extract of A. muricata at 500 microg/ml showed maximum scavenging activity (90.05%) of ABTS radical...

Ž . Alzheimer’s disease AD is an age-related, neurodegenerative disorder characterized by the presence of brainŽ . resident neurofibrillary tangles, senile plaques SP , and w x loss of synapses 9 . The major component of SP is the Ž . aggregated form of amyloid b-peptide A b , which is w x 39–43 amino acids in length 19 . A b is associated with free radical oxidative stress as demonstrated in m...

Phenolic compounds are widely distributed in the plant kingdom and microorganisms. Cinnamic acid its hydroxylated derivative-ferulic acid, phenolic compounds. Ferulic possesses antioxidant potential, as well anti-cancer, anti-inflammatory, antimicrobial properties. It prevents harmful effects of radiation both an ultraviolet absorber a free radical scavenger; it is not cytotoxic. Although ferul...