نتایج جستجو برای: fx rate
تعداد نتایج: 962675 فیلتر نتایج به سال:
A major limitation for adenoviral transduction in vivo is the profound liver tropism of adenovirus type 5 (Ad5). Recently, we demonstrated that coagulation factor X (FX) binds to Ad5-hexon protein at high affinity to mediate hepatocyte transduction after intravascular delivery. We developed novel genetically FX-binding ablated Ad5 vectors with lower liver transduction. Here, we demonstrate that...
Human adenoviruses from multiple species bind to coagulation factor X (FX), yet the importance of this interaction in adenovirus dissemination is unknown. Upon contact with blood, vectors based on adenovirus serotype 5 (Ad5) binds to FX via the hexon protein with nanomolar affinity, leading to selective uptake of the complex into the liver and spleen. The Ad5:FX complex putatively targets hepar...
Dear Editor, Patient-specific induced pluripotent stem (iPS) cells, generated from somatic cells of disease-affected individuals, hold a tremendous potential for studying disease mechanisms and for drug screening approaches using cell types previously not available (Yamanaka, 2008). Fragile-X (FX) syndrome belongs to the autism spectrum disorders, and is the most common cause of inherited menta...
I. DIFFERENTIAL ENTROPY AND THE GAUSSIAN CHANNEL A. Differential Entropy Let X be a random variable with a continuous alphabet. • FX(x) = Pr(X ≤ x) Cumulative Distribution Function {CDF}. F (x) is a short notation for FX(x). • fX(x) = dFX(x) dx Probability Density Function {PDF} (in this course we will assume that the derivative exists). f(x) is a short notation for fX(x). Definition 1 ( Differ...
1 Preliminaries Let fX t g be a discrete-time stochastic process. Throughout, we will assume that any process fX t g is indexed by the integers or some subset of the integers (for example, the positive integers). In practice, we observe a nite length sample (or time series) X 1 ; ; X n from fX t g. (In this presentation, we will distinguish between a stochastic process fX t g and a nite time se...
BACKGROUND Laminaria japonica has frequently been used as a food supplement and drug in traditional oriental medicine. Among the major active constituents responsible for the bioactivities of L. japonica, fucoxanthin (FX) has been considered as a potential antioxidant. This study was conducted to examine the effects of L. japonica extract (LJE) or FX against oxidative stress on hepatocytes and ...
A cDNA clone for factor 10 (FX) isolated from chicken embryo inserted into the mammalian cell expression vector pCDNA3.1 was transfected into the baby hamster kidney (BHK-21) cell line. The generated BHK-21 cells with inducible expression of FX were used to investigate the efficacy of the serine transmembrane protease to proteolytic activation of influenza virus hemagglutinin (HA) with monobasi...
Fructus Xanthii (FX) has been widely used as a traditional herbal medicine for rhinitis, headache, cold, etc. Modern pharmacological studies revealed that FX possesses anti-inflammatory, anti-oxidative, and anti-hyperglycemic properties. The present study was designed to investigate the effects of FX on glucose and insulin tolerance, and hepatic lipid metabolism in rats fed on high-fat diet (HF...
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