U.S. Air Force special tactics operators at times use small wearable computers (SWCs) for mission objectives. The primary pointing device of a SWC is either a touchpad or trackpoint, which is embedded into the chassis of the SWC. In situations where the user cannot directly interact with these pointing devices, the utility of the SWC is decreased. We developed a pointing device called the G3 th...

The aim of this study was to examine the therapeutic potential of sulfasalazine and prednisolone in a mouse collagen antibody-induced arthritis (CAIA) model. Twenty-five male BALB/c mice were randomly divided into five groups: group 1 (G1): control, group 2 (G2): probe control, group 3 (G3): CAIA, group 4 (G4): CAIA+sulfasalazine (10 mg/kg, oral), and group 5 (G5): CAIA+prednisolone (100 mg/kg,...

BACKGROUND Telomere shortening has been related to vascular dysfunction and hypertension. In the present study, we analyzed the influence of telomerase deficiency and telomere shortening on arterial pressure (AP). METHODS AND RESULTS AP was evaluated in 6-month-old mice lacking the RNA component of the telomerase (terc-/-) at the first generation and third generation (G3). First generation an...

For a graph G and a set F of connected graphs, G is said be F-free if G does not contain any member of F as an induced subgraph. We let G3(F) denote the set of all 3-connected F-free graphs. This paper is concerned with sets F of connected graphs such that |F| = 3 and G3(F) is finite. Among other results, we show that for an integer m > 3 and a connected graph T of order greater than or equal t...

For example, a woman who is described as 'gravida 2, para 2 (sometimes abbreviated to G2 P2) has had two pregnancies and two deliveries after 24 weeks, and a woman who is described as 'gravida 2, para 0' (G2 P0) has had two pregnancies, neither of which survived to a gestational age of 24 weeks. If they are both currently pregnant again, these women would have the obstetric résumé of G3 P2 and ...

BACKGROUND Poorly differentiated clusters (PDCs) at the invasive front of tumors in colorectal cancer (CRC) have recently been highlighted as histological prognosticators. We aimed to assess the clinical importance of extent of PDCs in CRC. METHODS A total of 239 patients with non-mucinous pT2 and pT3 CRC were pathologically reviewed. PDCs were defined as cancer clusters composed of ≥5 cancer...

Here, we report a case of gastric neuroendocrine carcinoma showing an interesting tumorigenic pathway. A 57-year-old Japanese woman presented with epigastric tenderness, and distal gastrectomy was performed. In the surgical specimen, histologically, the tumor tissue was composed of three subtypes of tumor components showing different histological architecture and cellular atypia, diagnosed as n...

BackgroundRecently, cell-based tissue engineering approaches using mesenchymal stem cells (MSCs) have been used to treat osteoarthritis (OA). However, the efficacy of human synovium-derived MSCs (hSD-MSCs) has not yet tested in a canine model OA. The purpose this study was investigate therapeutic effects intra-articular hSD-MSC injections OA model.MethodsSixty beagles underwent surgical manipul...

For example, a woman who is described as 'gravida 2, para 2 (sometimes abbreviated to G2 P2) has had two pregnancies and two deliveries after 24 weeks, and a woman who is described as 'gravida 2, para 0' (G2 P0) has had two pregnancies, neither of which survived to a gestational age of 24 weeks. If they are both currently pregnant again, these women would have the obstetric résumé of G3 P2 and ...