We investigated %CDT (carbohydrate-deficient transferrin) in 92 ethanol-intoxicated alcohol-dependent patients after consecutive admission to hospital and followed the for 28 days under controlled conditions. At admission, 63% (58 patients) showed elevated CDT (> 2.5%) and 34 patients (37%) had normal CDT levels (< 2.5%). No correlation of the %CDT values to alcohol-related disabilities, severi...

A pragmatic randomised trial examined the effects of Early Warning Signs Relapse Prevention Training (EWSRPT) on drinking in alcohol dependent persons with history of relapse. Participants were 124 abstinent alcohol dependent patients with a history of relapse (median five relapses) who entered the trial as they completed a 6-week day treatment programme. They were randomly allocated to receive...

OBJECTIVE To investigate risk factors, such as heavy alcohol consumption, that might explain any increased risk of haemorrhagic stroke associated with low blood cholesterol. DESIGN Prospective cohort study. SETTING Korea. PARTICIPANTS 787,442 civil servants (661,700 men, 125,742 women) aged 30-64. MAIN OUTCOME MEASURES Cardiovascular risk factors were assessed at biennial health check. ...

background: the knowledge of blood parameters is important for assessing the physiological status and health of animals. objectives: this study was conducted to determine the effect of heavy pregnancy on some serum indices of dromedary camels. methods: twenty clinically healthy female dromedary camels aged between 4-5 years were divided into two equal groups: i: pregnant camels in their last tr...

The research included isolation and purification of Trypsin from serum patient with pancreatic cancer, estimation its molecular weight by using the two techniques gel filtration (using sephadex G-50) electrophoresis SDS). Therefore; it was noted that proteinous peak isolated ammonium sulfate solution is saturated (65%) had apparent (27000) Dalton. study (40) patients pancreas cancer their ages ...

gamma-Glutamyl transpeptidase, a membrane-bound enzyme, functions in the gamma-glutamyl cycle to catalyze utilization of glutathione. It has been postulated that the amino-acid-stimulated utilization of glutathione by gamma-glutamyl transpeptidase reflects an aspect of amino acid translocation. As one approach to the effective in vivo inhibition of this enzyme, the inhibition of the enzyme by L...

Inhibitors for glutathione S-transferase (GST) iso-enzymes from rat liver with high affinity for the glutathione-binding site (G-site) have been developed. In previous studies, a model was described for the G-site of GST (Adang, A. E. P., Brussee, J., van der Gen, A., and Mulder, G. J. (1990) Biochem. J. 269, 47-54) in terms of essential and nonessential interactions between groups in glutathio...

Experimental evidence is presented that the determination of gamma-glutamyl transferase (GGT) activity in serum is useful in the assessment of alcohol-induced liver disease and for demonstrating to patients the toxic effects of their drinking habits on the liver. Serial measurements of GGT activity in serum have also proved valuable in monitoring the progress of therapy as well as alleged abste...