BACKGROUND Coarse bran is known to accelerate transit through the whole gut and to increase stool weight. This effect is much reduced by grinding the bran, suggesting that particle size influences gut motor patterns. AIMS To compare the effect of 15 g coarse bran with 15 g inert plastic particles and 7 g of ispaghula on the gastric emptying and small bowel transit of a rice pudding test meal....

It is generally believed that the hydrochloric acid solution secreted by the oxyntic cells is isotonic with the blood, and that the reduction of the acidity observed in the gastric juice is due to subsequent dilution and neutralization by other secretions (see Babkin, 1944). Teorell (1933), using anaesthetized or decerebrate cats whose stomachs were tied at both ends, observed a rapid decrease ...

It is widely accepted that gastric parameters such as gastric distention provide a direct negative feedback signal to inhibit eating; moreover, gastric and intestinal signals have been reported to synergize to promote satiation. However, there are few human data exploring the potential interaction effects of gastric and intestinal signals in the short-term control of appetite and the secretion ...

The endocrine, exocrine and paracrine secretions of the gastrointestinal (GI) tract play a pivotal role in the digestion and absorption of food and orally administered drugs. The secretion of mucus by mucus-secreting cells protects the erosion of the gastric mucosa from the highly acidic gastric juice. The secretion of hydrochloric acid from parietal cells is regulated by acetylcholine, histami...

In studying gastric secretion it has been customary to promote the flow of juice by some sort of artificial stimulus, whether food or drug, and such a procedure is of obvious importance where the digestive capabilities of the stomach are under consideration. There is, however, another aspect of stomach function which is of value in clinical medicine, namely an assay of the secretions under rest...

Summary Linked to the growing obesity epidemic, demand for bariatric and metabolic surgery has increased, most common procedures being sleeve gastrectomy Roux-en-Y gastric bypass. Originally, were described as purely restrictive, malabsorptive, or combined restrictive–malabsorptive limiting food intake, nutrient absorption, both. Nowadays, anatomical alterations are known affect gastro...

At an average of 32 days after a modified Roux-en-y repositioning of rat small intestine, the mucosal mass, mucosal composition, in vivo absorption of galactose and the activity of maltase, sucrase and alkaline phosphatase were measured. In the gut segment with digestive secretions but without food (A) the only change was a decrease of sucrase activity which occurred most probably at the cellul...

The elderly people have various physiological dysfunctions and the high morbidity rates as well as a high risk of malnutrition with many diseases. Gustatory dysfunction is also observed as a usual clinical problem in the elderly. In the elderly, elevation of the gustatory threshold for umami taste, as well as for salty, sweet, sour, and bitter tastes, has been confirmed. Glutamate (Glu), one of...

thyroid hormoned are known to influence acid and pepsin secretion,though exact mechanism(s) are not fully understood.in this study distention-stimulated acid and pepsin secretionof hypo and hyperthyroid rats were compared with controls.each group consisted of 8 N-mari rats from both sexs,weighing  246.6+_9.2g. hypo and hyper thyroid states were induced by administration of methimazole(500mg/l H...