Citation: Wilkinson TJ, Gould DW, Watson EL and Smith AC (2017) Commentary: Renal Function Estimation and Cockcroft–Gault Formulas for Predicting Cardiovascular Mortality in Population-Based, Cardiovascular Risk, Heart Failure and PostMyocardial Infarction Cohorts: The Heart ‘OMics’ in AGEing (HOMAGE) and the High-Risk Myocardial Infarction Database Initiatives. Front. Med. 4:77. doi: 10.3389/f...

Abstract Background The Cockcroft-Gault equation (CrClC-G) is recommended for dose adjustment of direct oral anticoagulant drugs (DOACs) to kidney function. We aimed assess whether defining DOACs appropriateness according various function estimators changed the associations between and adverse events in older adults with atrial fibrillation (AF). Methods Participants Berlin Initiative Study AF ...

INTRODUCTION Serum cystatin C is more sensitive for glomerular filtration rate (GFR) measurement, but it is not available for clinical use in all laboratories. Regarding the importance of accurate estimation of GFR in kidney transplant recipients, we compared cystatin C-based equations with creatinine-based formulas to estimate GFR as precisely and simply as possible in kidney transplant recipi...

BACKGROUND Earlier qualification for the kidney transplant waitlist expedites transplant and is therefore associated with improved outcomes. U.S. Organ Procurement and Transplantation Network policies state that "measured or calculated creatinine clearance or glomerular filtration rate less than or equal to 20 mL/min" triggers waitlist time accrual. The choice of qualification method is somewha...

Clinical guidelines suggest neoadjuvant cisplatin-based chemotherapy prior to cystectomy in the setting of muscle-invasive bladder cancer (MIBC). A creatinine clearance (CrCl) >60 mL/min is frequently used to characterize cisplatin-eligible patients, and use of the CKD-EPI equation to estimate CrCl has been advocated. From a prospectively maintained institutional database, patients with MIBC wh...