Objectives: To determine the correlations between measurements obtained with Heidelberg retina tomograph III (HRT III), optic coherence tomography (OCT), and laser polarimetry (GDx) indices of automated perimetry (AP) in moderate severe glaucoma patients. Methods: Forty-nine eyes 30 patients were included current study divided into two groups: 23 26 defined by Hodapp-Parrish-Anderson grading sy...

BACKGROUND The interaction of alcohol and testosterone has long been of interest, mainly due to the effect of alcohol on aggression and sexual behavior. To date, there have been very few, if any, studies examining the effect of acute alcohol administration on testosterone concentrations in the brain. The administration of 1,1-dideuteroethanol ([1,1-2H2]ethanol) provided the opportunity to trace...

AIM To assess the effect of gonadectomy on brain derived neurotrophic factor (BDNF) expression in neuropathic pain. METHODS Using chronic constriction injury (CCI) model, we detected BDNF mRNA in dorsal root ganglion and protein content in spinal cord by reverse transcription polymerase chain reaction and enzyme-linked immunosorbent assay respectively. The time point we chose was post CCI ope...

PURPOSE The GDx is a scanning laser polarimeter that assesses peripapillary nerve fiber layer thickness. In addition to the 14 existing outcome parameters, four new parameters have been described recently: the Ellipse Standard Deviation (ESD), the Normalized Superior Area (NSA), the Normalized Inferior Area (NIA) and the Discriminant Analysis (DA). The aim of this study was to investigate the s...

purpose: to examine the relationship between retinal nerve fiber layer (rnfl) measurements obtained using scanning laser polarimetry with variable corneal compensation (vcc) and central corneal thickness (cct) measurements using pentacam in myopic patients methods: the study included 45 eyes from 45 myopic patients with intraocular pressure (iop) measurements≤21 mmhg. all participants had norma...

To examine the hormonal and immunological mechanisms that mediate sex differences in susceptibility to malaria infection, intact and gonadectomized (gdx) C57BL/6 mice were inoculated with Plasmodium chabaudi AS-infected erythrocytes, and the responses to infection were monitored. In addition to reduced mortality, intact females recovered from infection-induced weigh loss and anemia faster than ...

Unilateral ligation of the tendon of anterior superficial part of rat masseter muscle (TASM) leads to long-lasting allodynia. Sex differences in peripheral mu-opioid receptor (MOR)-mediated analgesia under persistent myogenic pain are not well understood. In this study, we examined (1) whether locally applied MOR agonists attenuate persistent pain following TASM ligation in a sex dependent mann...

PURPOSE To evaluate the influence of disease severity and optic disc size on the diagnostic accuracy of three imaging technologies for structural assessment in glaucoma: confocal scanning laser ophthalmoscopy, scanning laser polarimetry, and optical coherence tomography. METHODS One hundred five patients with glaucoma and 61 normal subjects were recruited from the Diagnostic Innovations in Gl...

purpose : this study was designed to assess and compare the thickness of the peripapillar retinal nerve fiber layer (rnfl) in amblyopic and normal eyes in unilateral strabismic ambelyopia using scanning laser polarimeter. methods : scanning laser polarimetry was performed on 17 patients with unilateral strabismic amblyopia who had an absence of neurologic diseases or glaucoma with a minimum age...