نتایج جستجو برای: gene dosage

تعداد نتایج: 1231446  

Journal: :Genetics 1973
D Schwartz

The gene competition model, originally formulated from studies on the regulation of alcohol dehydrogenase activity in maize, is also applicable to the phenomenon of dosage compensation in Drosophila. The model accounts for the absence of dosage compensation in sex determination.

Journal: :Genetics 2002
Victoria L Browning Rebecca A Bergstrom Sandra Daigle John C Schimenti

Proper levels of gene expression are important for normal mammalian development. Typically, altered gene dosage caused by karyotypic abnormalities results in embryonic lethality or birth defects. Segmental aneuploidy can be compatible with life but often results in contiguous gene syndromes. The ability to manipulate the mouse genome allows the systematic exploration of regions that are affecte...

Journal: :Applied and environmental microbiology 2011
Shaoxiao Wang Aymé Spor Thibault Nidelet Pierre Montalent Christine Dillmann Dominique de Vienne Delphine Sicard

Adaptation is the process whereby a population or species becomes better fitted to its habitat through modifications of various life history traits which can be positively or negatively correlated. The molecular factors underlying these covariations remain to be elucidated. Using Saccharomyces cerevisiae as a model system, we have investigated the effects on life history traits of varying the d...

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