Generalized linear models are the most commonly used tools to describe the stimulus selectivity of sensory neurons. Here we present a Bayesian treatment of such models. Using the expectation propagation algorithm, we are able to approximate the full posterior distribution over all weights. In addition, we use a Laplacian prior to favor sparse solutions. Therefore, stimulus features that do not ...

We extend to the GIG case the Schrödinger-WienerGerstein-Mandelbrot real neuron model of the conditional probability density function (pdf) for the random time, T , that it takes the neuron’s post-synaptic potential to reach the spiking threshold when the realization of the random afferent excitation rate, Λ, assumes the value λ. Then we analyze how to maximize I(Λ;T ) per joule of energy the n...

Variability in single neuron models is typically implemented either by a stochastic Leaky-Integrate-and-Fire model or by a model of the Generalized Linear Model (GLM) family. We use analytical and numerical methods to relate state-of-theart models from both schools of thought. First we find the analytical expressions relating the subthreshold voltage from the Adaptive Exponential Integrate-andF...

The proposed device is an electronic circuit that mimics the neural network controlling fast eye movements, or saccades. The device simulates the signals produced by each neuronal population during the control of a horizontal saccade and allows for observing and recording. It will serve as a valuable teaching tool in the field of neural control. Furthermore, the device will have applications in...

introduction cholinergic system is one of the important systems of mammalian cns. cholinergic neurons distributed in brain and spinal cord and contributed to principal functions like: consciousness, learning and memory, and motor control. in this study we investigated the differentiation potentiality of mouse embryonic stem cells toward cholinergic neurons. the aim of this study was to evaluate...

objective(s) motor deficit and neuron degeneration is seen after nerve transection. the aim of this study is to determine whether a poled polyvinelidene fluoride (pvdf) tube with other supportive strategies can protect the neuronal morphology and motor function after sciatic nerve transaction in rats. materials and methods after transection of the left sciatic nerve in 60 male wistar rats (200-...

this paper addresses synchronizing two coupled chaotic fitzhugh–nagumo (fhn) neurons with weakly gap junction under external electrical stimulation (ees). to transmit information among coupled neurons, by generalization of the integer-order fhn equations of the coupled system into the fractional-order in frequency domain using crone approach, the behavior of each coupled neuron relies on its pa...

in this paper, a new class of multifunctions, called generalized alpha (mu_{x};mu_{ y} )-continuous multifunctions, has been dened and studied. some characterizations and severalproperties concerning generalized alpha (mu_{x};mu_{ y} )-continuous multifunctions are obtained. the re-lationships between generalized alpha (mu_{x};mu_{ y} )-continuous multifunctions and some known con-ce...

Spike-frequency adaptation is a prominent feature of neural dynamics. Among other mechanisms, various ionic currents modulating spike generation cause this type of neural adaptation. Prominent examples are voltage-gated potassium currents (M-type currents), the interplay of calcium currents and intracellular calcium dynamics with calcium-gated potassium channels (AHP-type currents), and the slo...

1 Neuronal hyper-synchrony is implicated in epilepsy and other diseases. The low frequency, spa2 tially averaged electric fields from many thousands of neurons have been shown to promote 3 synchrony. It remains unclear whether highly transient, spatially localized electric fields from 4 single action potentials (ephaptic coupling) significantly affect spike timing of neighboring cells 5 and, in...