Title: Rule based classifier for the analysis of gene-gene and gene-environment interactions in genetic association studies

applying an appropriate statistical analysis is complementary for conducting a robust experimental design in plant and animal breeding. in these experiments 33 iranian bread wheat genotypes, cultivated in a randomized complete blocks design with three replications in two normal and saline conditions were evaluated at the field of national salinity research center located in yazd province, iran....

PURPOSE OF REVIEW There is considerable variability in human body weight, despite the ubiquity of the 'obesogenic' environment. Human body weight has a strong genetic basis and it has been hypothesised that genetic susceptibility to the environment explains variation in human body weight, with differences in appetite being implicated as the mediating mechanism; so-called 'behavioural susceptibi...

complex inherited diseases affected by an interaction between collective effects of the genotype at one or multiple loci either to increase or to lower susceptibility to disease, combined with a variety of environmental exposures that may trigger, accelerate, exacerbate, or protect against the disease process. the new aspects of genetic techniques have been opened for diagnosis and analysis of ...

Using monthly test day records the genetic parameters of Iranian Holstein cattle in first lactation were studied. Data of 277400 test-day milk records from 65320 cows and 2210 sires were analyzed by an animal random regression model using restricted maximum likelihood methodology. The model included herd-test-date, interaction between year-season of calving, days in milk (linear and quadratic) ...

today multinational studies using genome-wide association scan (gwas) for >1000,000 polymorphisms on >100,000 cases with major psychiatric diseases versus controls, combined with next-generation sequencing have found ~100 genetic polymorphisms associated with schizophrenia (scz), bipolar disorder (bd), autism, attention deficit and hyperactivity disorder (adhd), etc. however, the effect size of...

Prior research suggests a link between academic performance and alcohol use during adolescence, but the degree to which this association reflects actual protective effects continues to be debated. We investigated the role of genetic factors in the association between academic achievement and adolescent alcohol use and whether achievement might constrain the translation of genetic influences on ...