Chicken genomics has benefited from the rapid technological advances in the genomics of model organisms and man. A number of resources and approaches are now well established, in the chicken, including genetic markers and maps (both genetic and physical), quantitative trait loci mapping, comparative mapping, expressed sequence tag and bacterial artificial chromosome resources, and physical mapp...

In most Genetic Programming (GP) approaches, the space of genotypes, that is the search space, is identical to the space of phenotypes, that is the solution space. Developmental approaches, like Developmental Genetic Programming (DGP), distinguish between genotypes and phenotypes and use a genotypephenotype mapping prior to fitness evaluation of a phenotype. To perform this mapping, DGP uses a ...

Recent research in pharmacogenomics has inspired our hope to predict drug response by linking it with DNA information extracted from the human genome. However, many genetic models of drug response do not incorporate biochemical principles of host-drug interactions, limiting the effectiveness of the predictive models. We argue that functional mapping, a computational tool aimed at identifying ge...

The nature of the mapping between the genotype and the phenotype is vital to the performance of a genetic algorithm. We develop the notion of a phlegmatic mapping function, which encapsulates the idea that small changes in the genotype ought to produce small changes in the phenotype. After illustrating a mapping function with this property, we validate the idea using a test suite of function op...