The pat ient was a female neonate bor n prematurely on 36 weeks of gestation by normal vaginal delivery. During pregnancy, mother had no history of fever, drug use or x-ray exposure. The mother was gravida 2 and had no history of abortion. Her first baby was well. On physical examination, the skin was markedly thickened, hard and hyperkeratotic with deep crevices running transversely and vertic...

Physical deformities have been a recurrent challenge on broiler production in the tropics. The effect of physical body deformity (PBD) differential growth 550 commercial chicks Ross308 strain from day-old to 56 days were evaluated. Experimental design was completely randomized Design (CRD), while treatment groups normal birds (NB), crooked neck (CN), twisted Leg (TL) and neck+twisted leg (CN+TL...

One suspected case of Wildervanck syndrome (OMIM 314600) reported from our tertiary care centre. is distinct other similar conditions due to its opthal and hearing associations-forming a clinical triad. Candidate gene identification in still pending whereas most genetic has got specific mutation. Klippel Feil anomaly one girl admitted centre with severe pneumonia showed features short neck, fus...

In mammals, embryonic development are highly regulated morphogenetic processes that are tightly controlled by genetic elements. Failure of any one of these processes can result in embryonic malformation. The lysyl oxidase (LOX) family genes are closely related to human diseases. In this study, we investigated the essential role of lysyl oxidase-like 3 (LOXL3), a member of the LOX family, in emb...

Background The etiology of Adolescent Idiopathic Scoliosis has been investigated for years. Now that the genetic basis for the disease has been established, the actual mechanism for production of the curve still needs to be discovered. Several have proposed a theory involving balance, with the brain and spinal cord causing spinal curvature related to neurologic signals [1,2]. An opportunity to ...

Abstract Background Although drug therapy for rheumatoid arthritis (RA) has recently improved, treating patients with established disease, whose hands have three major deformities (thumb deformity, finger deformities, and ulnar drift), remains a challenge. The underlying complex pathophysiology makes understanding these difficult, comprehensive assessment methods require accumulated skill long ...

COVID-19 has spread around the world rapidly. Outing restrictions are performed globally to prevent further of infection. A healthy 49-year-old man was taken in ambulance due severe dyspnea. For previous 10 days, he had been performing remote work at home mainly a sitting position outing for prevention spread. On admission, his blood pressure low and could not be measured by automated sphygmoma...

Background: Plastic deformity is a fixed deformity of bones after application of force which is in contrast to elastic deformity, so it remains unchanged. It is a rare condition and is seen more commonly in upper extremity (forearm). Inability to recognize it causes limitation of motion and remaining of angular deformity. It occurs more commonly in children because of flexibility of their bones...