نتایج جستجو برای: gilford progeria syndrome

تعداد نتایج: 622251  

2012
Leslie B. Gordon Kan Cao Francis S. Collins

Cell biologists love to think outside the box, pursuing many surprising twists and unexpected turns in their quest to unravel the mysteries of how cells work. But can cell biologists think outside the bench? We are certain that they can, and clearly some already do. To encourage more cell biologists to venture into the realm of translational research on a regular basis, we would like to share a...

2013
Seung-Jun Lee Sung-Ha Park

Arterial ageing is characterized by age associated degeneration and sclerosis of the media layer of the large arteries. However, besides ageing, clinical conditions, which enhance oxidative stress and inflammation act to accelerate the degree of arterial ageing. In this review, we summarized the pathophysiology and contributing factors that accelerate arterial ageing. Among them, we focused on ...

Journal: :The Korean Journal of Internal Medicine 2009
Yun Jeong Doh Hee Kyoung Kim Eui Dal Jung Seung Hee Choi Jung Guk Kim Bo Wan Kim In Kyu Lee

Hutchinson-Gilford progeria syndrome (HGPS) and Werner's syndrome are representative types of progeroid syndrome. LMNA (Lamin A/C) gene mutation with atypical Werner's syndrome have recently been reported. Atypical Werner's syndrome with the severe metabolic complications, the extent of the lipodystrophy is associated with A133L mutation in the LMNA gene and these patients present with phenotyp...

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