OBJECTIVE The aim of this study was to evaluate the antimicrobial activity of auxiliary chemical substances and natural extracts on Candida albicans and Enterococcus faecalis inoculated in root canals. MATERIAL AND METHODS Seventy-two human tooth roots were contaminated with C. albicans and E. faecalis for 21 days. The groups were divided according to the auxiliary chemical substance into: G1...

Problem statement:The fungal infections could be life-threatening in immunocompromised patients. Candida albicans is the most frequent fungi in the oral cavity. Approach: The first step for treatment could be done using topical antifungal agents. Nystatine is a choice for mentioned usage but there are some problems in its using including: unfavorite taste, frequency of usage, etc. Finding bette...

PURPOSE The aim of this study was to examine the antioxidant activity of ginger extract oral supplement in newly diagnosed cancer patients receiving adjuvant chemotherapy compared to placebo. PATIENTS AND METHODS Newly diagnosed cancer patients receiving moderate-to-high emetogenic potential adjuvant chemotherapy were randomized to receive either a ginger extract (standardized 6-gingerol 20 m...

background the hippocampus is responsible for memory. a diet full of antioxidants improves brain damage and cognitive function. regard the antioxidant effects of zingiber officinalis (ginger) and its flavonoids components. objectives the aim of this study was to evaluate the effect of the extract of ginger on memory by using hippocampus tissue of the male offspring of rats. materials and method...

Herbs and spices have been traditionally used for prevention and cure of many diseases. Hence, the present study was aimed to investigate the effects of aqueous and alcoholic extract of four different spices (asafoetida, ginger, cinnamon and cardamom) extracts on human breast adenocarcinoma cell line (MCF) and HEP-G2 cancer cell lines through in-vitro growth inhibitory assay. Both aqueous and a...

The rhizome of ginger (Zingiber officinale Roscoe) is known to have several bioactive compounds including gingerols and shogaols which possess beneficial health properties such as anti-inflammatory and chemopreventive effects. Based on recent observations that 6-shogaol may have more potent bioactivity than 6-gingerol, we obtained a 6-shogaol-rich extract from ginger and examined its effects on...

BACKGROUND Nausea and vomiting are common and unpleasant complications in pregnancy. Although many alternative therapists support the use of ginger for nausea and vomiting of pregnancy, there is currently insufficient clinical evidence to support its use in this condition. OBJECTIVES The present study was performed to assess the effectiveness of ginger in the treatment of nausea and vomiting ...

OBJECTIVE The main function of IL-12 is differentiation of naive T cells intoTh1 cells and TGF-β is a powerful immunoregulatory cytokine. The immunomodulatory and anti-inflammatory properties of ginger have also been reported in some studies. The aim of this study was to evaluate the effects of ginger extract on the expression of IL-12 and TGF-β in a model of experimental autoimmune encephalomy...

OBJECTIVE The spice Zingiber officinale or ginger possesses antioxidant activity and neuroprotective effects. The effects of this traditional herbal medicine on 3,4-methylenedioxymethamphetamine (MDMA) induced neurotoxicity have not yet been studied. The present study considers the effects of Zingiber officinale on MDMA-induced spatial memory impairment and apoptosis in the hippocampus of male ...

BACKGROUND Inflammation and pain induced by delayed onset muscle soreness (DOMS) as a result of eccentric exercise (EE) or unaccustomed activity cause some difficulties in exercise for athletes. The purpose of this study was to survey the effect of ginger extract on biochemical and functional symptom of delayed onset muscle soreness. METHODS In a quasi-experimental study, 36 healthy female su...