Background: With the increasing rate of oral diseases there is a progressive need for effective measures for prevention and provision of better oral health. Tooth brushes as a commercial and effective tools are available with different bristle textures, sizes, and forms. This study aims to compare the effect of soft, medium and hard bristle tooth brushes on oral hygiene, using oral hygiene indi...

OBJECTIVE To evaluate the prevalence of periodontal disease (PD) among Brazilian low-risk pregnant women and its association with sociodemographic factors, habits and oral hygiene. METHOD This cross-sectional study included 334 low-risk pregnant women divided in groups with or without PD. Indexes of plaque and gingival bleeding on probing, probing pocket depth, clinical attachment level and g...

Periodontitis is a multifactorial disease. Even though specific infectious agents are of key importance in the development of periodontitis, it is unlikely that a single agent or even a small group of pathogens are the sole cause or modulator of this heterogeneous disease. Due to the episodic nature of periodontal disease, viruses play an important role in etiology. The present review focusses ...

Introduction: Oral epithelium forms a physical, chemical and immunological barrier against the invading microorganisms. The mainly comprises of anti-microbial peptides (AMPs) like cathelicidins which are endogenously produced antibiotics. Transcription cathelicidin peptide (CAMP) gene is induced by binding bioactive form vitamin D to receptor. Thus, an increase in should significantly improve f...

statement of problem: in recent years, numerous reports have been presented in the literature, about gingival overgrowth induced by nifedipine- a calcium antagonist- prescribed for hypertension and certain types of angina. purpose: the purpose of the present study was to investigate the prevalence rate of nifedipine induced gingival hyperplasia in patients and its probable relationship with age...

Objectives. This study aimed to determine the association between some oral health status as a risk factor for cardiac diseases and other cardiovascular disease (CVD) risk factors in a sample of Iranian population in 2011. Methods. The study recruited 5900 inhabitants who aged 15-75 years old of Kerman city through a population based cluster sampling. Having collected informed consent, particip...

Periodontitis are diseases of the supportive tissues of the teeth provoked by bacteria and characterized by gingival inflammation and bone destruction. We have developed a new strategy to repair tissues by administrating agents (RGTA) that mimic heparan sulfates by protecting selectively some of the growth factors naturally present within the injured tissue and interfering with inflammation. Af...

Periodontal diseases are localized chronic inflammatory conditions of the gingival and underlying bone and connective tissue. Platelet-activating factor (PAF), a potent inflammatory phospholipid mediator that has been previously detected in elevated levels in inflamed gingival tissues, in gingival crevicular fluid and in saliva, is implicated in periodontal disease. Our results from previous st...

There are many etiological factors for nonplaque-induced gingival diseases, out of which physical trauma due to psychiatric reasons leading to self-infliction is less studied upon. This case report presents one such case which has been successfully treated stepwise where psychological counseling was done to restrain from habit followed by using an innovative laterally positioned periosteal pedi...

Hereditary gingival fibromatosis (HGF) is a rare disorder characterized by progressive and varying degrees of gingival overgrowth. Oral manifestations may vary from minimal involvement of only tuberosity area and the buccal gingiva around the lower molars to a generalized gingival enlargement. It can occur as an isolated disorder but can be one feature of a syndrome. Although the clinical and h...