نتایج جستجو برای: glomerulosclerosis

تعداد نتایج: 3958  

2006
M. G. Hanna R. W. Tennant J. M. Yuhas N. K. Clapp B. L. Batzing M. J. Snodgrass

The immune reactivity to endogenous (wild-type) RNA tumor virus-related antigen(s) was evaluated in RF mice, a strain with a low natural incidence of lymphoma. The purposes were to determine whether maintained humoral immunity could be detected and to evaluate the response with respect to the immune-mediated pathogenesis of glomerulosclerosis and incidence of tumors of lymphatic origin. Measure...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1992
J B Kopp M E Klotman S H Adler L A Bruggeman P Dickie N J Marinos M Eckhaus J L Bryant A L Notkins P E Klotman

Patients infected with human immunodeficiency virus type 1 (HIV-1) develop a renal syndrome characterized by proteinuria, renal failure, and focal segmental glomerulosclerosis. By using a noninfectious HIV-1 DNA construct lacking the gag and pol genes, three transgenic mouse lines have been generated that develop a syndrome remarkably similar to the human disease. In the present study, we have ...

Journal: :Journal of the American Society of Nephrology : JASN 2010
Thijs W Cohen Tervaert Antien L Mooyaart Kerstin Amann Arthur H Cohen H Terence Cook Cinthia B Drachenberg Franco Ferrario Agnes B Fogo Mark Haas Emile de Heer Kensuke Joh Laure H Noël Jai Radhakrishnan Surya V Seshan Ingeborg M Bajema Jan A Bruijn

Although pathologic classifications exist for several renal diseases, including IgA nephropathy, focal segmental glomerulosclerosis, and lupus nephritis, a uniform classification for diabetic nephropathy is lacking. Our aim, commissioned by the Research Committee of the Renal Pathology Society, was to develop a consensus classification combining type1 and type 2 diabetic nephropathies. Such a c...

Journal: :Diabetes 2008
Ying Qian Eva Feldman Subramanian Pennathur Matthias Kretzler Frank C Brosius

Progression of diabetic nephropathy to end-stage kidney disease is mediated by a host of processes, but none is as important as the gradual, inexorable scarring of the renal glomerulus, known as glomerulosclerosis. Hence, a host of studies over the decades have attempted to elucidate the molecular mechanisms that lead to this chronic sclerosing condition so that effective therapies and preventa...

Journal: :Nephrology Dialysis Transplantation 2003

Journal: :Nephrology Dialysis Transplantation 1998

Journal: :Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 2006
Li-Fen Zhang Shi-Li Cao Wen-Zheng Huang Yao-Guang Wang Xiao-Di Zhu

OBJECTIVE To investigate the effects of Shenshuning Recipe (SSNR) on gene expression of hepatocyte growth factor (HGF) in renal tissues in rats with glomerulosclerosis. METHODS Glomerulosclerosis was induced in 42 rats by unilateral nephrectomy and intravenous injection of doxorubicin. Then these 42 rats were randomly divided into three groups: untreated group, SSNR-treated group and benazepr...

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