Two immunologically distinct types of 22000-Mr subunits are present in rat lung glutathione S-transferases. One of these subunits is probably similar to Ya subunits of rat liver glutathione S-transferases, whereas the other subunit Ya' is immunologically distinct. Glutathione S-transferase II (pI7.2) of rat lung is a heterodimer (YaYa') of these subunits, and glutathione S-transferase VI (pI4.8...

background : progression of systemic lupus erythematosus (sle) could be due to oxidative stress especially through reactive oxygen species (ros). detoxification of ros is largely performed by glutathione s-transferases (gsts), therefore polymorphisms of gstm1, gstt1 and gstp1 genes which decrease enzymes activity could affect sle susceptibility. the aim of this study was to determine the effect...

background: glutathione s-transferases ( gsts ) have been investigated as potential carcinoma susceptible genes. however, the relationship between gsts ( gstm1 , gstt1 ) variants and gastric carcinoma (gc) risk has been controversial in chinese population. methods: a comprehensive literature search strategy (pubmed, chinese biomedical database, chinese national knowledge infrastructure, wan fan...

objective(s):to the best of our knowledge, this is the first report on the contributions of gst genetic variants to the risk of diabetic retinopathy in an iranian population. therefore, the objective of this study was to determine whether sequence variation in glutathione s-transferase gene (gstm1 and gstt1) is associated with development of diabetic retinopathy in type 2 diabetes mellitus (t2d...

background cellular level of enzyme activity can serve as a reliable biomarker in the event of environmental/chemical insults. objectives the present study investigated time-dependent alterations of erythrocyte glutathione s-transferase (ery-gst) activity of non-malarious guinea pigs (cavia tschudii) administered with pyrimethamine/sulfadoxine and artemether/lumefantrine combination therapies. ...

two-dimensional electrophoresis (2-d electrophoresis) is a powerful and extensively used method for analysis of complex protein mixtures extracted from cells, tissue, or other biological samples such as helminth parasites including, f. hepatica. each spot on the resulting two-dimensional collection corresponds to a single protein species in the sample. this study was carried out to detect of gs...

orchard workers in north china are highly exposed to orchard pollens, especially peach and other rosaceae family pollens during pollination season. the aim of this study was to investigate whether occupational allergy to peach tree pollen as a member of rosaceae family is ige-mediated and to evaluate the cross-reactivity among rosaceae family pollens. allergen skin test and conjunctival challen...