Early and regular blood transfusion therapy in patients with homozygous beta-thalassemia decreases the complications of severe anemia and prolongs survival. In the long term, however, the beneficial effects of transfusions are limited by the organ damage resulting from iron overload. Endocrine complications in patients with thalassemia major in developing countries may be frequent due t o ...

This study was conducted in the College of Agriculture - University Basra from 1/9/2020 to 15/1/2021 by collecting 120 blood samples males and females Arabi sheep breed, as well taking reproductive organs (testes ovaries) evaluate effect age, weight sex animals on sexual hormone levels . Samples were divided into three age groups (5-8 months, 9-12 months 1-1.5 years) body (15-25, 26-36, 37-47) ...

Work upon the assay of hormones in blood and urine has been progressive in volume and quality since Loewe (1) and Frank (2) demonstrated the presence of estrogenic hormone in blood. Loewe (3) then revealed that this substance is excreted cyclically in the urine. Such assays were made practicable by the work of Kahnt and Doisy (4) who standardized the procedure of assay for this hormone, using t...

BACKGROUND Iatrogenic transmission of human prion disease can occur through medical or surgical procedures, including injection of hormones such as gonadotropins extracted from cadaver pituitaries. Annually, more than 300,000 women in the United States and Canada are prescribed urine-derived gonadotropins for infertility. Although menopausal urine donors are screened for symptomatic neurologica...

Kisspeptin is a potent activator of GnRH-induced gonadotropin secretion and is a proposed central regulator of pubertal onset. In mice, there is a neuroanatomical separation of two discrete kisspeptin neuronal populations, which are sexually dimorphic and are believed to make distinct contributions to reproductive physiology. Within these kisspeptin neuron populations, Kiss1 expression is direc...

Parity in women is associated with reduced lifetime risk of breast cancer, and hormones of pregnancy [estrogen (E), progesterone (P), human chorionic gonadotropin (hCG)] are implicated. Parity also reduces mammary cancer risk in carcinogen-exposed rats, and administering pregnancy hormones to these animals is similarly effective. Because pregnancy hormones are also able to stimulate cancer grow...

In amphibians, as well as in other vertebrates, occytes start to mature under the action of hypophyseal gonadotropic hormones. (In this paper the term 'maturation' implies the transformation into ripe eggs of oocytes that have finished growing.) In the course of maturation the oocytes themselves and the follicle cells surrounding them undergo changes; the changes of these two cell types are not...