The glycophosphatidylinositol (GPI) anchors of proteins expressed on human erythrocytes and nucleated cells differ with respect to acylation of an inositol hydroxyl group, a structural feature that modulates their cleavability by PI-specific phospholipase C (PI-PLC). To determine how this GPI anchor modification is regulated, the precursor and protein-associated GPIs in two K562 cell transfecta...

BACKGROUND Carotid artery stenting (CAS) is a reasonable alternative to carotid endarterectomy (CEA), especially in patients at high risk for surgery. Carotid artery thrombosis of the treated segment is a rare, early but potentially devastating complication of this endovascular procedure. The aim of this article is to identify and critically review cases of acute stent thrombosis reported in th...

The rate of growth or decline in Gross Domestic Product (GDP) is reported quarterly in New Zealand and regarded as the ultimate measure of the current wealth and wellbeing of the nation. However, the economy is much greater than the exchanges that take place in the marketplace (which is the source of GDP statistics) and in reality cannot be separated from the people who produce and consume good...

The aim of this study was to assess progress in the field of anesthesia monitoring over the past 40 years using scientometric analysis. The following scientometric indexes were used: popularity indexes (general and specific), representing the proportion of articles on either a topic relative to all articles in the field of anesthetics (general popularity index, GPI) or the subfield of anesthesi...

Glycosylphosphatidylinositol (GPI)-specific phospholipases are highly valuable for studying the structure and function of GPIs. GPI-specific phospholipase C (GPI-PLC) from Trypanosoma brucei and phosphatidylinositol-specific phospholipase C (PI-PLC) from Bacillus cereus are the most widely studied of this class of phospholipases C. Inhibition of protein activity by thiol reagents is indicative ...

The family of tissue inhibitors of metalloproteinases (TIMPs) exhibits diverse physiological/biological functions including the inhibition of active matrix metalloproteinases, regulation of proMMP activation, cell growth, and the modulation of angiogenesis. TIMP-1 is a secreted protein that can be detected on the cell surface through its interaction with surface proteins. The diverse biological...

The implementation of teaching in the COVID-19 pandemic season has urged teachers to be more prepared and open face learning sessions (PdP) that require a comprehensive technology approach. Therefore, preparation readiness instrument for use PdP this study been adapted from several literature studies based on theories models used. main purpose is evaluate validity reliability preparedness accor...

Togetherness, molecular style O ne way to switch the function of a cell surface protein is to force it into a different membrane domain. On page 647, Nicholson and Stanners describe a second method: diluting it within its domain with an abundance of defective partners. The approach might provide a way to neutralize a protein that is over-produced in most cancers. Some surface proteins lie compl...