A 49-year-old woman with biopsy-proved bronchocentric granulomatosis (BCG) had repeated exacerbations of seronegative rheumatoid arthritis and vasculitis of the skin concurrent with BCG. To our knowledge, there have been no prior reports of this form of systemic involvement in BCG. While its pathogenesis remains obscure, this case, along with another recent report of eye involvement, suggests t...

Neurologic manifestations of lymphomatoid granulomatosis occur in 20-30% of cases. The disease is primarily an unusual form of pulmonary angiitis, and was first described in 1972 by Liebow et al. [1] . The purpose of this paper is to show the progression and regression of CNS lesions in a 17-year-old boy who presented only with neurologic features of the disease. Patients with lymphomatoid gran...

A 13-year-old boy with evidence of pulmonary lymphomatoid granulomatosis developed monocular diplopia. Fluorescein angiography revealed bilateral choroidal involvement. Following treatment with vincristine, cyclophosphamide, and prednisone his diplopia resolved and the angiographic appearances returned to normal.

A patient with lymphomatoid granulomatosis and focal transformation to lymphoma limited to the central nervous system presented with severe central neurogenic hyperventilation. The hyperventilation resolved as the underlying pathologic condition was treated with prednisone and cyclophosphamide.

Orofacial granulomatosis (OFG) is an uncommon condition that presents as non-tender, non-pruritic, chronic oral labial swelling. It is a diagnosis of exclusion, and requires a full systemic workup to exclude other causes of granulomatous inflammation, such as Crohn’s disease, sarcoidosis, and tuberculosis. The cause of OFG is unknown, and there is significant debate as to whether it is in fact ...

Orofacial granulomatosis is a chronic granulomatous condition characterized by relapsing and remitting lip swelling and oral involvement that may include deep ulcers, tags and cobblestone formation. It occurs as an independent entity but also in conjunction with systemic diseases such as tuberculosis, sarcoidosis and Crohn's disease. The clinical presentation is not indicative of concomitant sy...

Orofacial granulomatosis (OFG) is a granulomatous disease of the orofacial region which appears usually as a persistent and/or recurrent labial soft tissue swelling in the orofacial region and is characterized histologically by a granulomatous inflammation. OFG may cause significant cosmetic and functional problems but can be prevented if the disease is diagnosed early and promptly treated. Thi...

Lymphomatoid granulomatosis usually presents as a primary lung affliction with secondary metastatic spread to the central nervous system(CNS), and its initial manifestation purely as a CNS disease is rare. A 57-year-old man with histologically proven lymphomatoid granulomatosis of the brain as the sole manifestation of the disease is presented.

Lymphomatoid granulomatosis is an uncommon disorder that can present as multiple pulmonary nodules. Systemic manifestations such as fever, weight loss, skin lesions, and other organ involvement may occur. The clinical presentation of lymphomatoid granulomatosis can mimic infectious diseases (eg, tuberculosis), vasculitis, or metastatic malignancies.1 Lymphomatoid granulomatosis should be consid...