Although green tea is considered to be a healthy beverage, hepatotoxicity associated with the consumption of green tea extract has been reported. In the present study, we characterized the hepatotoxicity of green tea extract in rats and explored the responsible mechanism. Six-week-old IGS rats received a single intraperitoneal (ip) injection of 200 mg/kg green tea extract (THEA-FLAN 90S). At 8,...

There is mounting evidence that the deposition and aggregation of β-amyloid peptides (Aβ) in the brain play a significant role in the development and pathogenesis of Alzheimer's disease. There is further evidence that free radical species such as hydrogen peroxide (H(2)O(2)) mediate Aβ induced toxicity. Previous studies have demonstrated that green tea polyphenols possess neuroprotective proper...

the effect of green tea, echinacea purpurea, rosemary extracts on dilation of oxidation and rancidity development in broiler thigh meat was studied. therefore, fresh thighs were dipped in 0.1%  alcoholic aqueous extract during 15 min and kept frozen (-20°c) until 6 months. sampling was carried out at 1, 30, 60, 90, 120,150 and 180 days of aging at -20°c. a parallel experiment with ascorbic acid...

Multidrug resistance and various adverse side effects have long been major problems in cancer chemotherapy. Recently, chemotherapy has gradually transitioned from mono-substance therapy to multidrug therapy. As a result, the drug cocktail strategy has gained more recognition and wider use. It is believed that properly-formulated drug combinations have greater therapeutic efficacy than single dr...

Peptic ulcer is a common disorder of the stomach and duodenum. Herbs and medicinal plants are considered to be a potential source to combat various diseases including gastric ulcer. The present study was conducted to evaluate the gastro protective effects of Echinacea extract, Green tea extract and Boswellia extract on a pyloric ligation-induced gastric ulcer. Six groups of rats were intraperit...

Green tea polyphenols may contribute to the prevention of cancer and other diseases. To learn more about the pharmacokinetics and interindividual variation of green tea polyphenols after oral intake in humans we performed a population nutrikinetic study of standardized green tea extract. 84 healthy participants took green tea extract capsules standardized to 150 mg epigallocatechin-gallate (EGC...

Green tea has been reported to show anti-inflammatory properties because of its inhibitory effects on the expression of several pro-inflammatory genes. Because the inducible nitricoxide synthase (iNOS) plays an important role in chronic inflammatory diseases, we have focused our attention on the regulation of iNOS expression by green tea in two different human epithelial cell lines, alveolar A5...

Background: The recruitment of medicinal herbs for the treatment of psychological disorders such as anxiety and stress has a long history. The purpose of the present study was to investigate the compensatory effects of hydroalcoholic extract of green tea on anxiety behaviors that are induced by noise stress in male Wistar rats. Methods: In this study, male Wis...

to evaluate the most suitable method as well as different conditions of blanching in the process of green tea production from local tea green leaves, this research was conducted in split plot in time and on the basis of a randomized complete block design of six treatments in 3 replications (different plucking times). two common methods of blanching by steaming and panning were used. green leaf ...