The dysmyelinating mutant jimpy (jp) arises from a point mutation in the mouse gene encoding proteolipid protein and is characterized by severe dysmyelination attributable to oligodendrocyte death. This mutant was used to investigate the regulation of oligodendrocyte progenitor proliferation in the postnatal spinal cord. At postnatal day 18, jp spinal cord contained a three- to eightfold greate...

GRO J2058+42 is a 195 s transient X-ray pulsar discovered in 1995 with BATSE. In 1996, RXTE located GRO J2058+42 to a 90% confidence error circle with a 4 radius. On 20 February 2004, the region including the error circle was observed with Chandra ACIS-I. No X-ray sources were detected within the error circle, however, 2 faint sources were detected in the ACIS-I field-of-view. We obtained optic...

The ability of tumor cells to metastasize is associated with a poor prognosis for cancer. During the process of metastasis, tumor cells circulating in the blood or lymph vessels can adhere to, and potentially transmigrate through, the endothelium and invade the connective tissue. We studied the effectiveness of the endothelium as a barrier against the invasion of 51 tumor cell lines into a thre...

The repetitive X-ray bursts from the accretion-powered pulsar GRO J1744−28 show similarities to the type II X-ray bursts from the Rapid Burster. Several authors (notably Lewin et al.) have suggested that the bursts from GRO J1744−28 are type II bursts (which arise from the sudden release of gravitational potential energy). In this paper, we present another similarity between these sources. Ross...

The unusal hard x-ray burster GRO J1744-28 recently discovered by the Compton Gamma-ray Observatory (GRO) can be modeled as a strange star with a dipolar magnetic field ≤ 10 11 Gauss. When the accreted mass of the star exceeds some critical mass, its crust may break, resulting in conversion of the accreted matter into strange matter and release of energy. Subsequently, a fireball may form and e...

The orbital parameters of the recently discovered transient burster/pulsar GRO J1744–28 indicate that this system is a low-mass X-ray binary in an advanced stage of its mass transfer, with several tenths of a solar mass already transferred from the donor to the compact star. All neutron stars known to have accreted such an amount have very weak magnetic fields, and this has led to the idea that...

Using the RXTE PCA we discovered dips in the X-ray light curves of the black-hole candidate GRO J1655−40 during outburst. They are short (∼minute) and deep (down to ∼8% of the out-of-dip intensity). Similar kind of dips were found in 90 s measurements of the RXTE ASM during the same outburst. The occurrences of the dips are consistent with the optically determined orbital period, and were found...

The purpose of this study is to investigate the effectiveness of the HIPO planning and optimization algorithm for real-time prostate HDR brachytherapy. This study consists of 20 patients who underwent ultrasound-based real-time HDR brachytherapy of the prostate using the treatment planning system called Oncentra Prostate (SWIFT version 3.0). The treatment plans for all patients were optimized u...

We summarize five years of continuous monitoring of accretion-powered pulsars with the Burst and Transient Source Experiment (BATSE) on the Compton Gamma Ray Observatory. Our 20–70 keV observations have determined or refined the orbital parameters of 13 binaries, discovered 5 new transient accreting pulsars, measured the pulsed flux history during outbursts of 12 transients (GRO J1744–28, 4U 01...

We summarize 5 years of continuous monitoring of accretion-powered pulsars with the Burst and Transient Source Experiment (BATSE) on the Compton Gamma Ray Observatory. Our 20È70 keV observations have determined or reÐned the orbital parameters of 13 binaries, discovered Ðve new transient accreting pulsars, measured the pulsed Ñux history during outbursts of 12 transients (GRO J1744[28, 4U 0115]...