Background & Aim: The treatment of Parasagittal Meningioma (PSM) is always a challenge, especially when the tumor has already invaded the critical structures like venous sinuses. This study aims at evaluating the outcomes of Gamma Knife Radiosurgery (GKRS) in patients with PSM. Methods and Materials/Patients: In this descriptive retrospective study, we reviewed the medical records of 61 patien...

To evaluate the rationality and limitations of the seventh edition of the American Joint Committee on Cancer (the 7th AJCC edition) T-staging system for locally advanced nasopharyngeal carcinoma (NPC). The prognosis of 358 patients with stage T3/T4 NPC treated with intensity-modulated radiotherapy (IMRT) was analyzed with the Kaplan-Meier method or the log-rank test. The 7th AJCC staging system...

OBJECTIVE To study the feasibility and the potential benefits of defining the internal gross tumor volume (IGTV) of hepatocellular carcinoma (HCC) using contrast-enhanced 4D CT images obtained by combining arterial-phase (AP) contrast-enhanced (CE) 3D CT and non-contrast-enhanced (NCE) 4D CT images using deformable registration (DR). METHODS Ten HCC patients who had received radiotherapy befo...

Staging and radiotherapy planning Given the limitations of CT for adequate detection of lesions in many tumor types, functional and molecular imaging is used for improved detection of lesions and assessment of loco-regional disease that should be included in the radiation treatment plan [1,2]. This may result in an increase as well as a decrease of the gross tumor volume (GTV). Increasing the G...

Objective The objective of this study was to investigate the safety of robotic stereotactic body radiation therapy (SBRT) for hepatocellular carcinoma (HCC) patients and its related factors. Methods A total of 74 HCC patients with Child-Turcotte-Pugh (CTP) Class A were included in a multi-institutional, single-arm Phase II trial (NCT 02363218) between February 2013 and August 2016. All patien...

PURPOSE To see the gross tumor volume (GTV) dependency according to the phase selection and reconstruction methods, we measured and analyzed the changes of tumor volume and motion at each phase in 20 cases with lung cancer patients who underwent image-guided radiotherapy. MATERIALS AND METHODS We retrospectively analyzed four-dimensional computed tomography (4D-CT) images in 20 cases of 19 pa...

tumour volume and clinical target volume among various radiation oncologists, which can potentially lead to variation in tumor control or adverse effects. Interobserver variation can reduce with experience or by utilizing additional facilities such as CT–MRI fusion or CT–PET fusion. Several publications have reported that MRI and PET scans [Figures 1 and 2] can significantly change the tumor vo...

PURPOSE To determine the optimal standardized uptake value (SUV) of (18)F-fluorodeoxyglucose ((18)F-FDG) for positron emission tomography (PET) imaging, at which the PET-defined gross tumor volume (GTVPET) best matches with the pathological volume (GTVPATH) in the cervical cancer. MATERIALS AND METHODS Ten patients with the cervical cancer who underwent surgery were enrolled in this study. Th...

PURPOSE To assess the effectiveness of two automated magnetic resonance imaging (MRI) segmentation methods in determining the gross tumor volume (GTV) of brain tumors for use in radiation therapy treatment planning. METHODS AND MATERIALS Two automated MRI tumor segmentation methods (supervised k-nearest neighbors [kNN] and automatic knowledge-guided [KG]) were evaluated for their potential as...

PURPOSE Magnetic resonance image (MRI) guided radiotherapy enables gating directly on the target position. We present an evaluation of an MRI-guided radiotherapy system's gating performance using an MRI-compatible respiratory motion phantom and radiochromic film. Our evaluation is geared toward validation of our institution's clinical gating protocol which involves planning to a target volume f...