نتایج جستجو برای: growth differentiation factor 9b gdf9b

تعداد نتایج: 1620112  

Abdolamir Allameh, Maryam Jazayeri Masoud Soleimani, Saeid Kaviani Seyed Hamid Jazayeri Somaieh Kazemnejad

Human bone marrow derived mesenchymal stem cells (HBMSCs) have the potential to differentiate into cells such as adipocyte, osteocyte, hepatocyte and endothelial cells. In this study, the differentiation of hBMSCs into endothelial like-cells was induced in presence of vascular endothelial growth factor (VEGF) and insulin-like growth factor (IGF-1). The differentiated endothelial cells were exam...

Journal: :Circulation research 2013
Alexandra C McPherron

In an intriguing new study, Loffredo et al report that joining the circulation of old mice with that of young mice reduces age-related cardiac hypertrophy. They also found that the growth factor growth/differentiation factor 11 is a circulating negative regulator of cardiac hypertrophy which suggests that raising growth/differentiation factor 11 levels may be useful to treat cardiac hypertrophy...

Farah Zaker, Masoud Soleimani, Mohammad Hossein Tahmasbi, Mohammad Taghi Joghataei, Seyed Akbar Moosavi, Seyed Amir Yazdanparast,

New blood forming vessels are produced by differentiation of mesodermal precursor cells to angioblasts that become endothelial cells (ECs) which in turn give rise to primitive capillary network. Human cord blood (HCB) contains large subsets of mononuclear cells (MNCs) that can be differentiated into endothelial-like cells in vitro. Human mononuclear progenitor cells were purified from fresh umb...

2017
Hongmei Zhang Weiwei Zhang Xiaofang Tu Yixin Niu Xiaoyong Li Li Qin Zhen Yang Qing Su

In order to investigate whether serum growth differentiation factor 15 is associated with thyroid nodules in type 2 diabetes. We recruited 723 type 2 diabetic patients aged over 30 years who attended the clinic of Endocrinology of Xinhua Hospital from January 2013 to January 2015. Thyroid nodule was diagnosed by thyroid ultrasonographic examination. Serum growth differentiation factor 15, thyro...

Journal: :Cancer research 1993
R L Sparks B J Allen A I Zygmunt E E Strauss

Nontransformed 3T3 T mesenchymal/proadipocyte stem cells can be readily induced to differentiate, yet previous work has shown that 3T3 T cells that are spontaneously or virally transformed not only lose their normal growth control mechanisms but also lose the ability to differentiate. Loss of growth control can be due to autocrine mechanisms in some transformed cells, but the mechanisms involve...

Journal: :world journal of plastic surgery 0
ehsan fayazzadeh tehran heart center, tehran university of medical sciences, tehran, iran hana yavarifar school of medicine, ankara university, ankara, turkey seyyed reza rafie department of plastic and reconstructive surgery, 15 khordad hospital, shahid beheshti university of medical sciences, tehran, iran sadrollah motamed department of plastic and reconstructive surgery, 15 khordad hospital, shahid beheshti university of medical sciences, tehran, iran maryam sotoudeh anvari tehran heart center, tehran university of medical sciences, tehran, iran mohammad ali boroumand tehran heart center, tehran university of medical sciences, tehran, iran

background one of the main challenges in skin flap surgery is tissue ischemia and following necrosis. the present study compares the effects of fibroblast growth factors 1 and 2 on increasing cutaneous vasculature, improving ischemia, and preventing distal necrosis in ischemic skin flaps in rat model. methods thirty rats were allocated into 3 groups (n=10) and 2×8 cm dorsal random-pattern skin ...

Journal: :iranian journal of basic medical sciences 0
hamid reza asgari department of anatomy, faculty of medicine, tehran university of medical sciences, tehran, iran mohammad akbari department of anatomy, faculty of medicine, tehran university of medical sciences, tehran, iran mehdi abbasi department of anatomy, faculty of medicine, tehran university of medical sciences, tehran, iran jafar ai department of tissue engineering, school of advanced technologies, tehran university of medical sciences, tehran, iran morteza korouji department of anatomy, faculty of medicine, iran university of medical sciences, tehran, iran fereshte aliakbari department of anatomy, faculty of medicine, tehran university of medical sciences, tehran, iran

objective(s): the present day challenge is how to obtain germ cells from stem cells to treat patients with cancer and infertility. much more efforts have been made to develop a procedure for attaining germ cells in vitro. recently, human umbilical cord-derived mesenchymal stem cells (humscs) have been introduced with higher efficacy for differentiation. in this work, we tried to explore the eff...

Journal: :Investigative ophthalmology & visual science 2001
P A Folger D Zekaria G Grotendorst S K Masur

PURPOSE Transforming growth factor beta1 (TGF-beta) stimulates the differentiation of myofibroblasts as indicated by the nascent expression of alpha-smooth muscle (alpha-SM) actin protein and its organization into stress fibers. Downstream messengers of TGF-beta in the conversion from the fibroblast to the myofibroblast phenotype were investigated. Whether TGF-beta increases the transcription o...

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