The tetrahedral [NiII4L6]8+ cage can reversibly bind paramagnetic MX41/2? guests, inducing magnetic exchange interactions between host and guest.

The fibrous architecture of the extracellular matrix (ECM) is recognized as an integral regulator cell function. However, there unmet need to develop mechanically robust biomaterials mimicking nanofibrous tissue topography that are also injectable enable minimally invasive delivery. In this study, we have developed a hydrogel composed supramolecularly assembled hyaluronic acid (HA) nanofibers e...

Soft attachment of streptavidin to β-cyclodextrin-modified pegylated SAMs was efficiently performed in a reversible and repetitive way via orthogonal bifunctional linkers involving streptavidin-biotin recognition and redox-driven multivalent host-guest (β-cyclodextrin-ferrocene) interactions.

Recently, methine dyes have attracted interest for their possible application in display devices [1, 2 ] . A liquid crystal display based on the ability of "guest"' pleochroic dyes to align parallel to the "host" liquid crystal was first described by Heilmeier and Zanoni [3 ] . Since then the basic properties of "guest-host" type liquid crystal display devices and the effects of various paramet...

The C-ethyl-2-methylresorcinarene (1) forms 1:1 in-cavity complexes with aromatic N,N'-dioxides, only if each of the aromatic rings has an N-O group. The structurally different C-shaped 2,2'-bipyridine N,N'-dioxide (2,2'-BiPyNO) and the linear rod-shaped 4,4'-bipyridine N,N'-dioxide (4,4'-BiPyNO) both form 1:1 in-cavity complexes with the host resorcinarene in C4v crown and C2v conformations, r...

EUDOC is a docking program that has successfully predicted small-molecule-bound protein complexes and identified drug leads from chemical databases. To expand the application of the EUDOC program to supramolecular chemistry, we tested its ability to reproduce crystal structures of small-molecule complexes. Of 161 selected crystal structures of small-molecule guest-host complexes, EUDOC reproduc...

Two new 9,9'-spirobifluorene-derived crown ethers were prepared and used to recognise constitutionally isomeric amino acid derivatives. The performance of the receptors was evaluated by ESI-mass spectrometry using the isomer labelled guest method (ILGM). This method revealed the preferred binding of L-norleucine and L-leucine compared to L-isoleucine for both receptors. Furthermore, non-covalen...

We have synthesised a neutral, water-soluble, Pt(II) complex able to aggregate more efficiently in aqueous solutions than in organic solvents. The aggregates are luminescent and are not quenched by molecular oxygen. Further, we have prepared phosphorescent hydrogels utilising host-guest interactions between cyclodextrins and the tetraethylene glycol tails of the Pt(II) complex. The soft assembl...

A new bis(disulfide)-linked offset dimer is formed from a dithiolated analogue of cyclotriguaiacylene. Unlike a similar tris(disulfide)-linked example, this is not a true cryptophane as the offset nature of the dimerisation and intramolecular host-guest interactions preclude its use as a host.

Host-guest interactions are an attractive approach to design redox electrolytes, enabling precisely tune the key properties for flow batteries such as half-cell potential, solubility, and stability. Herein we report a host-guest complex of highly water soluble (2-hydroxypropyl)-β-cyclodextrin with 1-decyl-1′-ethyl-4,4′-bipyridinium dibromide anolyte in new aqueous organic battery (AORFB). The s...