experts from 31 countries met to discuss the challenges and innovations afforded by clinical practice guidelines. 1 Although each country faces unique local challenges to the implementation of effective health care, members of the guideline community have repeatedly and generously shared their solutions to these challenges, many of which are applicable in other countries. Nevertheless, it can b...

The year 2014 has certainly been a busy and rewarding year for the journal. It has been dominated by planning and organizing a journal development course for the editors and staff and the celebration of our anniversary, 35 years of continuous publication. On this occasion, we honored the historical achievements of the journal with an official ceremony in the presence of General Director of Medi...

This document presents official recommendations of the American Association for the Study of Liver Diseases (AASLD) on the surveillance, diagnosis, and treatment of hepatocellular carcinoma (HCC) occurring in the setting of adults with cirrhosis. Unlike previous AASLD practice guidelines, the current guideline was developed in compliance with the Institute of Medicine standards for trustworthy ...

The Academy of Medicine (AMS) and Ministry of Health (MOH) have developed the clinical practice guidelines on Assessment and Management of Infertility at Primary Healthcare Level to provide doctors and patients in Singapore with evidence-based treatment for infertility. This article reproduces the introduction and executive summary (with recommendations from the guidelines) from the AMS-MOH cli...

The Society of Surgical Oncology surgical practice guidelines focus on the signs and symptoms of primary cancer, timely evaluation of the symptomatic patient, appropriate preoperative extent of disease evaluation, and the role of the surgeon in diagnosis and treatment. Separate sections on adjuvant therapy, follow-up programs, or management of recurrent cancer have been intentionally omitted. W...

Introduction ................................................................................................................... 1295 I. Assessing the Clinical Benefits of Optimized PGS-Aneuploidy Screening Techniques ........................................................................................................ 1298 II. Contemporary Legal Doctrines Governing a Physician’s Standard of ...

BACKGROUND AND PURPOSE Conformal radiotherapy has only recently been widely implemented. Although not all aspects have yet been adequately proven, it is generally recognized that maintaining a high degree of precision throughout the process is critical to the treatment outcome while the focus for quality assurance and quality improvement will need to concentrate more on human factors, procedure...

Many complications after renal transplantation can be prevented if they are detected early. Guidelines have been developed for the prevention of diseases in the general population, but there are no comprehensive guidelines for the prevention of diseases and complications after renal transplantation. Therefore, the Clinical Practice Guidelines Committee of the American Society of Transplantation...

This document reflects emerging clinical and scientific advances on the date issued and is subject to change. The information should not be construed as dictating an exclusive course of treatment or procedure to be followed. Local institutions can dictate amendments to these opinions. They should be well documented if modified at the local level. None of these contents may be reproduced in any ...