نتایج جستجو برای: haemophilia a

تعداد نتایج: 13432458  

Journal: :BMC Blood Disorders 2004
Rumena Petkova Stoian Chakarov Ivo Kremensky

BACKGROUND Haemophilias are the most common hereditary severe disorders of blood clotting. In families afflicted with heamophilia, genetic analysis provides opportunities to prevent recurrence of the disease. This study establishes a diagnostical strategy for carriership determination and prenatal diagnostics of haemophilia A in Bulgarian haemophilic population. METHODS A diagnostical strateg...

Journal: :Hong Kong medical journal = Xianggang yi xue za zhi 2011
W Y Au Vincent Lee Bonnie Kho Alvin S C Ling Desmond Chan Eric Y T Chan Godfrey C F Chan Winnie W W Cheung C W Lau C Y Lee Rever C H Li C K Li S Y Lin Vivien Mak Lina Sun Kris H F Wong Raymond Wong Jeffrey Yau H L Yuen

OBJECTIVE To provide a synopsis of current haemophilia care in Hong Kong. DESIGN Retrospective survey. SETTING All haematology units of the Hospital Authority in Hong Kong. PATIENTS All patients with haemophilia A and haemophilia B. RESULTS To date, there were 222 mild-to-severe haemophilia patients (192 type A, 30 type B) under regular public care in Hong Kong (43% were considered seve...

Journal: :Haemophilia : the official journal of the World Federation of Hemophilia 2016
M Pai N S Key M Skinner R Curtis M Feinstein C Kessler S J Lane M Makris E Riker N Santesso J M Soucie C H T Yeung A Iorio H J Schünemann

This guideline was developed to identify evidence-based best practices in haemophilia care delivery, and discuss the range of care providers and services that are most important to optimize outcomes for persons with haemophilia (PWH) across the United States. The guideline was developed following specific methods described in detail in this supplement and based on the GRADE (Grading of Recommen...

Journal: :Haemophilia : the official journal of the World Federation of Hemophilia 2011
B O Mahony L Savini J O Hara A Bok

INTRODUCTION The European Haemophilia Consortium (EHC) is an international non-profit organization representing 45 national patients' organizations in Europe. Every 3 years, the EHC circulates a survey to its national member organizations to assess the state of haemophilia care. AIM The purpose of this exercise is to ascertain information about the organization of haemophilia care and treatme...

Journal: :Nature 2014

Journal: :Haemophilia : the official journal of the World Federation of Hemophilia 2012
A Grogan M Coughlan B O' Mahony G McKee

It has long been advocated that patient input in service quality development is essential. We have developed a model of quality evaluation and improvement within a comprehensive haemophilia service, and describe the issues and improvements that resulted from the process. The project utilized an action research methodology. Seven patients were recruited from the haemophilia service for the initi...

Journal: :Haemophilia : the official journal of the World Federation of Hemophilia 2011
A K Hegeman F R Van Genderen S Meijer M M Van Den Briel R Y J Tamminga E Van Weert

With the introduction of prophylaxis, restricting children with haemophilia to participate in physical activities was no longer necessary. Subsequently, many studies report on improved physical functioning in children and adolescents with haemophilia. However, little is known about psychological aspects such as perceived competence and impact of disease. Therefore, the aims of this study were t...

Journal: :Haemophilia : the official journal of the World Federation of Hemophilia 2012
J-L Poon Z-Y Zhou J N Doctor J Wu M M Ullman C Ross B Riske K L Parish M Lou M A Koerper F Gwadry-Sridhar A D Forsberg R G Curtis K A Johnson

This study describes health-related quality of life (HRQoL) of persons with haemophilia A in the United States (US) and determines associations between self-reported joint pain, motion limitation and clinically evaluated joint range of motion (ROM), and between HRQoL and ROM. As part of a 2-year cohort study, we collected baseline HRQoL using the SF-12 (adults) and PedsQL (children), along with...

2017
Sandra B van Os Nick A Troop Keith R Sullivan Daniel P Hart

INTRODUCTION haemophilia is an inherited bleeding disorder caused by a deficiency in one of the blood coagulation factors. For people affected by severe haemophilia, the deficiency can cause spontaneous internal bleeding. Most young people with severe haemophilia in the UK follow a preventative treatment regimen (prophylaxis) consisting of several intravenous injections of factor concentrate ea...

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