Phloretin [3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan1-one] is a hydrophobic, dihydrochalcone, polyphenolic compound (MW 274.3 g/mol, XlogP 2.6) that has been identified in apples and other natural sources including Pieris japonica, Kalmia latifolia, Hoveniae Lignum, and Loiseleuria procumbens [1-6] (Figure 1). Phloridzin is the glycoside of phloretin (phloretin-2’-glucose) which has ...

OBJECTIVES To formulate a polyherbal formulation and evaluate its antiarthritic activity against Freund's complete adjuvant induced arthritis in Female Wistar rats. MATERIALS AND METHODS Glycosmis pentaphylla, Tridax procumbens, and Mangifera indica are well-known plants available throughout India and they are commonly used for the treatment of various diseases including arthritis. The polyhe...

In an attempt to scientifically appraise the ‘healing powers’ and medicinal value of Harpagophytum procumbens DC root aqueous extract (HPE), and throw some light on the efficacy and safety of the medicinal plant product, the cardiovascular effects of the herb’s root aqueous extract (HPE) have been investigated in some mammalian experimental animal models. The results of this laboratory animal s...

UNLABELLED Modulation of cytokine secretion may offer novel approaches in the treatment of a variety of diseases. One strategy in the modulation of cytokine expression may be through the use of herbal medicines. A class of herbal medicines, known as immunomodulators, alters the activity of immune function through the dynamic regulation of informational molecules such as cytokines. This may offe...

Karyotypes of ten sections of genus Trigonella Linnaeus, 1753 (Fabaceae) from Turkey were investigated. Somatic chromosome numbers of examined species were determined as 2n=14 and 16. The karyotype analyses of the species were carried out and somatic chromosome numbers of Trigonella plicata Boiss., 1872, Trigonella brachycarpa (Fisch.) Moris, 1833, Trigonella rostrata Boiss., 1872, Trigonella l...

PURPOSE The leaves of Gynura procumbens (Lour.) Merr. has been traditionally used as anticancer. Ethanolic extract of G. procumbens leaves (EGP) showed cytotoxic activity and anticancer activity in animal cancer model. This study was conducted to observe antiproliferative effect using male rat's liver cells induced by 7,12-dimethylbenz(a)antracene (DMBA). METHODS Forty days old Sprague Dawley...

1 Past land use can have long-term e€ects on plant species' distributional patterns if alterations in resources and environmental conditions have persistent e€ects on population demography (environmental change) and/or if plants are intrinsically limited in their colonization ability (historical factors). 2 We evaluated the role of environmental alteration vs. historical factors in controlling ...