The effect of a daily dose of 400 mug beclomethasone dipropionate aerosol intranasally has been investigated in a double-blind cross-over trial in 29 patients with hay fever. The effect on the nasal symptoms was so pronounced in 25 patients that further symptomatic treatment was unnecessary. Beclomethasone dipropionate aerosol had, on the other hand, no direct effect on itching in the eyes, whi...

Cutaneous sensitivity to histamine, responses to prick tests with allergens, and serum IgE concentrations were measured and hay fever assessed by questionnaire in an unselected population to determine whether increased sensitivity to histamine is an independent phenomenon contributing to allergic disorders or may be caused by allergic reactions. Increased cutaneous sensitivity to histamine was ...

Three hundred patients with grass pollen hay-fever, with or without pollen asthma, were given one of three forms of treatment: preseasonal or coseasonal alum-precipitated pyridine extracted grass pollen (Allpyral) or methylprednisolone acetate in slow-release form (Depo-Medrone). Significant improvement was obtained with preseasonal Allpyral and with Depo-Medrone, but the degree of improvement ...

0 27. With hypertonic peritoneal dialysis his weight decreased by 1 6 kg, but blood pressure remained raised at 230/130 mm Hg, and the next day he suffered two generalised seizures. Packed cell volume was 0-35. Phenytoin was started. He was discharged on 17 December, normotensive with no neurological sequelae, and taking no antihypertensive medication. Phenytoin was subsequently withdrawn. He h...

The authors reply: We appreciate the additional points raised by Rao et al. and would underscore the importance of early initiation of antitoxin treatment in cases of suspected botulism. A retrospective analysis of 132 cases of foodborne botulism reported to the CDC from 1973 through 1980 showed a median hospital stay of 10 days if patients received antitoxin within 24 hours after symptoms bega...

Shall our state legislature be allowed to take that which is not their own, to turn it from its original use, and apply it to such ends or purposes as they, in their discretion, shall see fit? Sir, you may destroy this little institution; it is weak; it is in your hands! You may put it out, but if you do, you must carry on your work! You must extinguish, one after another, all those great light...

The observation that ABO agglutinins are present in a wide variety of pollens (Denborough, 1964) and so must commonly be inhaled, and the knowledge that plant agglutinins are antigenic (Mikela, 1957), prompted us to study secretor status in allergic disease of the respiratory tract, namely in asthma and hay fever. The opportunity has been taken to measure the amount of isoagglutinins present in...

The effects of change of residence on pollinosis symptoms remain unclear. We investigated the effects of geographical change of residence on pollinosis symptoms among university freshmen. All freshmen (n = 2142) entering Shinshu University in 2011 completed self-administered questionnaires. Associations between history of pollinosis and environmental factors were assessed. Subjects were classif...