Methods Plasma concentrations were modeled for patients treated with CAN (n = 50) or PBO after CAN treatment (n = 50) and used to predict flare risk by a validated and qualified simulation of the CAN exposure-flare hazard relationship. The model considered both PBO and CAN treatments and multiple covariates, including baseline steroid dose, heterogeneity of the population with respect to diseas...

Abstract Hazard maps are essential tools to aid decision makers in land-use planning, sustainable infrastructure development, and emergency preparedness. Despite the availability of historical data, there has been no attempt produce hazard for Kuwait. In cooperation with World Bank, this study investigated natural anthropogenic hazards that affect The objective was assess face Kuwait map most c...

Rivers are important water resources for human life, but sometimes cause irreparable damages. The flood plains are fertile terrains which are endangered by flood. Flood hazard mapping is one of the basic methods in flood fighting. In order to decline flood damages, the simulation of the hydraulic behavior of the rivers during flood occurrence is very important. In this study, areas that are flo...

This paper address the problem of Bayesian estimation of the parameters, reliability and hazard function in the context of record statistics values from the two-parameter Lomax distribution. The ML and the Bayes estimates based on records are derived for the two unknown parameters and the survival time parameters, reliability and hazard functions. The Bayes estimates are obtained based on conju...

Any driver behavior that draws the driver’s attention away from the roadway may increase the chance of a crash. This study developed a procedure to simulate safety impacts associated with driver distraction due to various secondary tasks. The simulation models a rear end hazard scenario where a lead vehicle suddenly decelerates while a driver is engaged in a secondary task. The simulation was t...

This paper presents a simulation framework for recreating the realistic safety hazard scenarios commonly observed in robotic surgical systems, which can be used to prepare surgical trainees for handling safety-critical events during procedures. The proposed simulation platform is composed of a surgical simulator based on an open-source surgical robot platform, Raven II, integrated with a softwa...

Many fires and explosions happen in tank farm. A fire and explosion simulation method based on VR is used. Tank fire and explosion special effect is realized by classical particle system. The real-time fire growth model, fireball growth model, fireball heat radiation model are created. The shock wave model of BLEVE also is created. The models and results of FDS (Fire Dynamic Simulator) are buil...

This paper develops omnibus tests for comparing cause-speciic hazard rates and cumulative incidence functions at speciied covariate levels. Conndence bands for the diierence and the ratio of two conditional cumulative incidence functions are also constructed. The omnibus test is formulated in terms of a test process given by a weighted diierence of estimates of cumulative cause-speciic hazard r...