BACKGROUND Detection of hepatitis B virus (HBV) genomes without detectable hepatitis B surface antigen (HBs-Ag) is termed occult HBV infection (OHBV) that may be transmitted by blood transfusion or organ transplantation and has acute reactivation when an immunosuppressive status like human immunodeficiency virus (HIV) infection occurs. We aimed to evaluate OHBV in HIV-infected patients with iso...

With more than two billion infected people, from whom 350 to 400 million suffer from chronic infection, hepatitis B virus (HBV) is still a major health problem worldwide. As dental treatment puts both dentists and patients at a higher risk of HBV infection, dentists can play an important role in preventing HBV transmission in dental settings. This study was performed to evaluate dental students...

BACKGROUND Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are major global public health problems. This study was conducted to investigate the incidence rate of these infections over six successive years in Hamadan Province, the west of Iran. METHODS This retrospective cohort study was conducted on the database of hepatitis registry. In this study, 1257 subjects infected by HB...

BACKGROUND Although certain HBV mutations are known to affect the expression of Hepatitis e antigen, their association with HBV viral level or clinical outcomes is less clear. OBJECTIVES We evaluated associations between different mutations in the Basal Core promoter (BCP) and Pre-core (PC) regions of HBV genome and subsequent changes in HBV viral DNA level over seven years in a population of...

Objective(s) The aim of this study was to characterize the hepatitis B virus surface protein genotypes and sequence variations among hepatitis B virus surface antigen (HBsAg) positive chronic patients in Hormozgan province, south of Iran. Materials and Methods A total of 8 patients enrolled in this study. The surface gene was amplified and directly sequenced. Genotypes and nucleotide/amino a...

Background: Gastrointestinal (GI), liver, and pancreaticobiliary diseases, in addition to the high health care utilization, account for a significant proportion of disability death Iran. We aimed assess incidence in-hospital mortality total GI, diseases all hospitals Kerman, Methods: In cross-sectional study from May 2017 April 2018, we collected data records due Kerman city. GI liver were clas...

I read with interest the recently published article by Ramezani et al. [1] in your journal. The issue is important but all the aspects and clinical importance of the study are not clear. According to an international workshop on occult hepatitis B virus infection (OBI) in 2008 [2], OBI is defined as the presence of HBV DNA in the liver (with detectable or undetectable HBV DNA in the serum) of i...

Background & Objectives: Hepatitis B is one of the major health problems in the world. Health care workers (HCWs) are at high risk of acquiring hepatitis B virus. The aim of this study was to evaluate the prevalence of HBV infection and the immune response to HBV vaccine among the HCWs in Babol, northern...

background: in patients who are hepatitis b virus (hbv) dna-positive, but hbv surface antigen (hbsag) -negative, the infection is referred to as occult hepatitis b infection (obi). occult hbv infection is harmful when other liver diseases are present, and can aggravate liver damage in in patients with chronic liver diseases. in human immunodeficiency virus (hiv) infection the suppression of vir...