نتایج جستجو برای: hcc
تعداد نتایج: 14224 فیلتر نتایج به سال:
BACKGROUND Mixed fibrolamellar hepatocellular carcinoma (mFL-HCC) is a rare liver tumor defined by the presence of both pure FL-HCC and conventional HCC components, represents up to 25% of cases of FL-HCC, and has been associated with worse prognosis. Recent genomic characterization of pure FL-HCC identified a highly recurrent transcript fusion (DNAJB1:PRKACA) not found in conventional HCC. P...
The G protein-coupled receptor, class C, group 5, member A (GPRC5A) plays a key role in various diseases, but its effect on hepatocellular carcinoma (HCC) and the potential underlying mechanisms remains unclear. In present study, we explored of GPRC5A progression HCC further mechanism action. results revealed that expression was lower tissues cells. Overexpression suppressed proliferation epith...
Inguinal hernias are common diseases, but malignant lesions in groin rare; metastatic hepatocellular carcinoma (HCC) the hernia sac is extremely rare. We report a 72-year-old man who had advanced stage HCC with portal vein invasion and multiple lymphadenopathies. He presented painless palpable mass right groin. Computed tomography scan showed contrast-enhanced soft tissue (2.8 cm size) at herni...
Background and AimsThe growing knowledge of ferroptosis has suggested the regulatory role in hepatocellular carcinoma (HCC), but pertinent molecular mechanisms remain unclear. Herein, this study investigated mechanistic basis ferroptosis-related genes (ferrGenes) growth HCC.
Abstract Background Hepatocellular carcinoma (HCC) represents the sixth most common cancer worldwide and fourth in Egypt. Persistent inflammation specific somatic mutations driving genes play a major role development of HCC. One these is CTNNB1 with subsequent activation β-catenin HCC, associated risk malignant transformation. In this study, we investigate clinical utility peripheral blood circ...
BACKGROUND Non-alcoholic fatty liver disease (NAFLD) is becoming a leading cause of chronic liver disease. Hepatocellular carcinoma (HCC) is one of its complications. Although the pathophysiology is unclear, it is reasonable to expect that cryptogenic cirrhosis related HCC (cryptogenic HCC) behaves differently to other types of HCC. This study prospectively compared patients with cryptogenic HC...
The basic unit of chromatin is a nucleosome included an octamer of the four core histones and 147 base pairs of DNA. Posttranslational histones modifications affect chromatin structure resulting in gene expression changes. CpG islands hypermethylation within the gene promoter regions and the deacetylation of histone proteins are the most common epigenetic modifications. The aberrant patterns of...
UNLABELLED The aim of this study was to identify a biomarker that could improve alpha-fetoprotein (AFP) performance in hepatocellular carcinoma (HCC) surveillance among patients with cirrhosis. We performed proteomic profiling of plasma from patients with cirrhosis or HCC and validated selected candidate HCC biomarkers in two geographically distinct cohorts to include HCC of different etiologie...
HBV is a risk factor for poor patient prognosis after curative resection of hepatocellular carcinoma
Controversy exists regarding pathological factors affecting the prognosis of hepatocellular carcinoma (HCC) patients with hepatitis B virus (HBV-HCC). Their postoperative clinical behaviors and the exact HBV Deoxyribonucleic Acid (DNA) thresholds that distinguish good and poor prognoses are unknown. This study aimed to compare clinicopathological, pre- and postoperative clinical factors and ove...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید