Introduction: During intensity modulated radiation therapy (IMRT) technique, theoretically, presence of flattening filter (FF) across the beamline of clinical linear accelerator (linac) is not essential to obtain uniform lateral profiles due to intensity modulation of photon beams by multileaf collimators (MLCs). The aim of this study was to investigate the dosimetrical propert...

The purpose of this study is to report the dosimetric aspects of commissioning performed on an Elekta Versa HD linear accelerator (linac) with high-dose-rate flattening filter-free (FFF) photon modes and electron modes. Acceptance and commissioning was performed on the Elekta Versa HD linac with five photon energies (6 MV, 10 MV, 18 MV, 6 MV FFF, 10 MV FFF), four electron energies (6 MeV, 9MeV,...

The MCNP Monte Carlo radiation transport code was used for calculation of scatter distribution and scatter-toprimary ratio (SPR) for different tube voltages, phantom thicknesses and field size in diagnostic radiology. Subsequently, the effect of grid’s design parameters such as strip density, grid ratio, interspace material and lead-tointerspace ratio on scatter rejection was investigated by ca...

Introduction: In radiation therapy with high-energy photon beams (E > 7 MeV) neutrons are generated mainly in LINACs head thorough (γ, n) interactions. These neutrons affect the shielding requirements in radiation therapy rooms. According to the protocol TG-34, photon absorbed dose of 10Gy can cause permanent damage to the pacemaker and the dose of 2Gy can make minor changes in...

Background: During intensity modulated radiation therapy (IMRT) technique, theoretically, presence of flattening filter (FF) across the beamline of clinical linear accelerator (linac) is not essential to obtain uniform lateral profiles due to intensity modulation of photon beams by multileaf collimators (MLCs). The aim of this study was to investigate the dosimetrical properties of 18 MV photon...

We have simulated the head geometry of a Varian Clinac 2100C/2300C medical accelerator in a Monte Carlo calculation to produce photoneutrons and transport them through the head shielding into a typical therapy room (modeled by a test cell at Varian Associates). The fast neutron leakage fluence and energy spectra have been calculated at 7 positions around the linac head for typical beam operatio...

Introduction: Gamma Knife is an instrument specially designed for treating brain disorders. In Gamma Knife, there are 201 narrow beams of cobalt-60 sources that intersect at an isocenter point to treat brain tumors. The tumor is placed at the isocenter and is treated by the emitted gamma rays. Therefore, there is a high dose at this point and a low dose is delivered to the normal tissue surroun...

For transmission computed tomography (TCT) systems using a centered transmission source with a fan-beam collimator, the transmission projection data are truncated. To achieve sufficiently large imaging field of view (FOV), we have designed the combination of an asymmetric fan-beam (AsF) collimator and a small uncollimated sheet-source for TCT, and implemented AsF sampling on a two-head SPECT sy...

Purified human peripheral blood polymorphonuclear neutrophils (PMN) were incubated at 37 degrees C with the fluorescent membrane potential sensitive cyanine dye di-O-C(5)(3) and exposed to a number of stimulatory agents (N-formylmethionylleucylphenylalanine (FMLP), cytochalasin B (cyto B) + FMLP, phorbol myristate acetate (PMA). Flow cytometry was utilized to measure changes in forward light sc...

introduction: gamma knife is an instrument specially designed for treating brain disorders. in gamma knife, there are 201 narrow beams of cobalt-60 sources that intersect at an isocenter point to treat brain tumors. the tumor is placed at the isocenter and is treated by the emitted gamma rays. therefore, there is a high dose at this point and a low dose is delivered to the normal tissue surroun...