Methylenetetrahydrofolate reductase (MTHFR) deficiency is a rare autosomal recessive disorder. A novel homozygous MTHFR c.474A>T (p.G158G) mutation was detected in two unrelated children of Jewish Bukharian origin. This mutation generates an abnormal splicing and early termination codon. A carrier frequency of 1:39 (5/196) was determined among unrelated healthy Bukharian Jews. Given the disease...

KEY II X Deadinferred carrier Q Chromosomes normal a couple who presented at a sub-fertility clinic with a history of two spontaneous abortions and no live born children after three years of marriage. Examination revealed a healthy 23-year-old female and a 27-year-old male, neither of whom had any previous relevant medical history. In addition to the two original spontaneous abortions, at 8 and...

The aim of this study was to evaluate the absolute risk for children younger than 4 years of age with asymptomatic oropharyngeal carriage of Kingella kingae to sustain an osteoarticular infection. The rate of K. kingae carriage in the oropharyngeal mucosa was 9% among healthy children, and the risk for an asymptomatic carrier to develop an osteoarticular infection due to K. Kingae was estimated...

The intersection of two contemporary trends – interest in fitness as a healthy lifestyle and the multitude of smartphone applications that seem able to serve any of our daily needs – was bound to produce an “explosion of health and fitness apps” [1]. But how well do these apps support the regimen of areas such as strength training or weightlifting, which are seeing significant growth and intere...

In this paper, a 7-level Diode Clamped Multilevel Inverter (DCMLI) is simulated with three different carrier PWM techniques. Here, Carrier based Sinusoidal Pulse Width Modulation (SPWM), Third Harmonic Injected Pulse Width Modulation (THIPWM) and Modified Carrier-Based Space Vector Pulse Width Modulation (SVPWM) are used as modulation strategies. These modulation strategies include Phase Dispos...

Aim The objective of this study was to examine the carrier status of theileriosis among apparently healthy cross-bred jersey cattle population of Odisha using conventional blood smear examination and polymerase chain reaction (PCR). Materials and Methods A total of 34 apparently healthy cross-bred Jersey lactating cows were considered in this study. Blood samples were subjected to microscopic...

We measured HBsAg/IgG complexes (CX) quantitatively by ELISA from HBsAg positive serum of 35 liver disease patients, 15 patients with glomerular diseases (8 membranous glomerulonephritis (MGN) 7 membranoproliferative glomerulonephritis (MPGN), and 50 healthy carriers of HBsAg. HbsAg/IgG CX was detected in 26 out of 35 liver disease patients (74.3%), 5 out of 50 healthy carriers (10%), and one o...

Presymptomatic DNA testing for autosomal dominant hereditary breast/ ovarian cancer (HBOC) became an option after the identification of the BRCA1 and BRCA2 genes in 1994-1995. Healthy female mutation carriers have a high lifetime risk for breast cancer (56-87%) or ovarian cancer (10-60%) and may opt for intensive breast and ovary surveillance or prophylactic surgery (mastectomy/ oophorectomy). ...

The PER2 gene has been reported to influence diurnal preference. In this study, we have attempted to characterize the associations between the PER2 gene polymorphisms and diurnal preference in a population of healthy young subjects, controlling for the social and environmental confounding factors. Subjects were 299 students in a college, carefully selected to be mentally and physically healthy....

A total of 630 apparently healthy volunteers were studied for seromarkers of hepatitis A and B by Enzyme Linked Immunosorbent Assay (ELISA) and Radioimmunoassay (RIA) techniques. A carrier rate of 5.3% for hepatitis B surface antigen (HBsAg) was found in young medical students while 10.7% recruits were positive for HBsAg. The pregnant females had HBsAg carrier rate of 7.8%. About 96.6% of young...