BACKGROUND Early stage breast cancer patients are long-term survivors and finding techniques that may lower acute and late radiotherapy-induced toxicity is crucial. We compared dosimetry of wedged tangential fields (W-TF), tangential field intensity-modulated radiotherapy (TF-IMRT) and multi-beam IMRT (MB-IMRT) in prone and supine positions for whole-breast irradiation (WBI). METHODS MB-IMRT,...

BACKGROUND Inclusion of inhomogeneity corrections in intensity modulated small fields always makes conformal irradiation of lung tumor very complicated in accurate dose delivery. OBJECTIVE In the present study, the performance of five algorithms via Monte Carlo, Pencil Beam, Convolution, Fast Superposition and Superposition were evaluated in lung cancer Intensity Modulated Radiotherapy planni...

Purpose/objective(s): To evaluate the dosimetric feasibility of a hypofractionated radiotherapy schedule for Stage III non-small cell lung cancers (NSCLC). Materials/Methods: The study sample included 14 cases. The mean tumor burden (primary and nodal areas) was 111 cm3, range 10-424 cm3. Intended plans consist of an initial dose of 40 Gy in 10 fractions, followed by a 7 Gy x 5 boost. The clini...

PURPOSE The purpose of this study was to explore the correlation between the respiration-induced target motion and volume variation with the dosimetric variance on breast and organ at risk (OAR) during free breathing. METHODS AND MATERIALS After breast-conserving surgery, seventeen patients underwent respiration-synchronized 4DCT simulation scans during free breathing. Treatment planning was ...

background: to suggest south india ct diagnostic reference levels (drls) by collecting radiation doses for the most commonly performed ct examinations. materials and methods: a pilot study investigated the most frequent ct examinations. 110 ct sites were asked to complete a survey booklet to allow the recording of ct parameters for each of 3 ct examinations during a 1 year time period. dose dat...

BACKGROUND The purpose of this study was to investigate the potential dose reduction to the heart, left anterior descending (LAD) coronary artery and the ipsilateral lung for patients treated with tangential and locoregional radiotherapy for left-sided breast cancer with enhanced inspiration gating (EIG) compared to free breathing (FB) using the AAA algorithm. The radiobiological implication of...

Treatment planning for breast cancer has been traditionally based on clinical landmarks. The Radiation Therapy Oncology Group (RTOG) published consensus guidelines on contouring target volumes (TV) for the breast/chest wall and draining lymphatics. The effect of these guidelines on dosimetric parameters in surrounding organs at risk (OAR) and TVs is unknown. Fourteen patients treated with clini...

PURPOSE This study investigated the trade-off in tumor coverage and organ-at-risk sparing when applying dose escalation for concurrent chemoradiation therapy (CRT) of mid-esophageal cancer, using radiobiological modeling to estimate local control and normal tissue toxicity. METHODS AND MATERIALS Twenty-one patients with mid-esophageal cancer were selected from the SCOPE1 database (Internation...