نتایج جستجو برای: heart entry
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OBJECTIVE To assess the effect of bezafibrate on the risk of coronary heart disease and stroke in men with lower extremity arterial disease. DESIGN Double blind placebo controlled randomised trial. SETTING 85 general practices and nine hospital vascular clinics. PARTICIPANTS 1568 men, mean age 68.2 years (range 35 to 92) at recruitment. INTERVENTIONS Bezafibrate 400 mg daily (783 men) o...
In this paper we describe the £ndings of an exploratory study of the effect of obstructive sleep apnea (OSA) on the electrocardiogram (ECG) signal. Episodes of sleep apnea are characterized by periodic cycles of breathing cessation and restoration. Our analysis was guided by the hypothesis that these cycles synchronously alter the ECG. We discovered several characteristic indicators of apnea in...
In many vertebrate and invertebrate cells, inositol 1,4,5-trisphospate production induces a biphasic Ca2+ signal. Mobilization of Ca2+ from internal stores drives the initial burst. The second phase, referred to as store-operated Ca2+ entry (formerly capacitative Ca2+ entry), occurs when depletion of intracellular Ca2+ pools activates a non-voltage-sensitive plasma membrane Ca2+ conductance. De...
RATIONALE The Na+ / K+ ATPase (NKA) directly regulates intracellular Na+ levels, which in turn indirectly regulates Ca2+ levels by proximally controlling flux through the Na+ / Ca2+ exchanger (NCX1). Elevated Na+ levels have been reported during heart failure, which permits some degree of reverse-mode Ca2+ entry through NCX1, as well as less efficient Ca2+ clearance. OBJECTIVE To determine wh...
missouri.edu/podcast/. Accessed March 4, 2005. 9. Ashton KC. Nurses, women, and heart disease. 2005. Available at: http://creekspace.net/nsdemo/index.htm. Accessed July 21, 2005. 10. Maag M. The potential use of “blogs” in nursing education. Comput Inform Nurs. 2005;23(1):16–24. 11. Wu D. The iPod photo goes medical. December 4, 2004. Available at: http://www.engadget.com/entry/1234000713024391...
The effect of quinidine on unidirectional fluxes of Na and K in isolated rabbit atria has been investigated and correlated with known effects of the drug on the electrical and mechanical properties of the heart. Quinidine caused a rapid inhibition of J\a entry, which secondarily depressed K efflux. In addition, the drug depressed membrane permeability to K and caused a marked inhibition of acti...
The human respiratory system is the gateway of entry for inhaled detritus from anthropogenic (e.g. combustionderived (CD) particulate matter (PM; e.g. diesel exhaust and wood-burning PM). Adult humans inhale 20m 3 of air and suspended debris (gases and particles) into the airways daily. Inhalation exposure to CDPM (Figure 1) is known to increase the risk of morbidity and mortality of lung and h...
In adults a tachycardia is any heart rate greater than 100 beats per minute. Supraventricular tachycardias may be divided into two distinct groups depending on whether they arise from the atria or the atrioventricular junction. This article will consider those arising from the atria: sinus tachycardia, atrial fibrillation, atrial flutter, and atrial tachycardia. Tachycardias arising from re-ent...
Treatment of cardiovascular diseases remains challenging considering the limited regeneration capacity of the heart muscle. Developments of reprogramming strategies to create in vitro and in vivo cardiomyocytes have been the focus point of a considerable amount of research in the past decades. The choice of cells to employ, the state-of-the-art methods for different reprogramming strategies, an...
The First Physical Therapy Summit on Global Health was convened at the 2007 World Confederation for Physical Therapy (WCPT) Congress to vision practice in the 21st century and, in turn, entry-level education and research, as informed by epidemiological indicators, and consistent with evidence-based noninvasive interventions, the hallmark of physical therapy. The Summit and its findings were inf...
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