Background: Clarithromycin resistance is an increasing problem in this part of the world and it potentially has an impact on the eradication rate of first line triple therapy (proton pump inhibitorAmoxicillinClarithromycin) for Helicobacter pylori (H. pylori) infection. Objective: This study was designed to determine the effect of clarithromycin resistance on the efficacy of Pantoprazole-Amoxic...

Helicobacter pylori infection alone or in combination with other factors is an important factor predisposing to dyspeptic disorders. Eradication of H. pylori fully eliminated dyspeptic syndrome or reduced its severity in the presence of concomitant factors. The efficacy of H. pylori eradication after first line therapy amounted to 85-90% based on the results of 13C-urease breath test, i.e. resi...

Since acceptance of the association between Helicobacter pylori and peptic ulcer disease, eradication of H. pylori has become the standard of care in the treatment of peptic ulcer disease. Unfortunately, eradication therapy is no easy task, especially when one is faced with a myriad of drug combinations with varying degrees of efficacy and tolerability. The following is a review of the literatu...

Objectives To examine the association between Helicobacter pylori infection and non-ulcer dyspepsia, and to assess the effect of eradicating H pylori on dyspeptic symptoms in patients with non-ulcer dyspepsia. Design Systematic review and meta-analysis of (a) observational studies examining the association between Helicobacter pylori infection and non-ulcer dyspepsia (association studies), and ...

Background and Objective: Different studies have investigated the link between helicobacter pylori and extra digestive diseases such as idiopathic thrombocytopenic purpura. However, the relationship between ITP and H pylori is less clear. Most of the studies have focused on H pylori eradication in chronic ITP, so we focused on the effect of H pylori eradication on chronicity of ITP in adult pat...

Helicobacter pylori (H. pylori) infection is the main cause of peptic ulcer disease (PUD), mucosa associated lymphoid tissue lymphoma, and gastric cancer (Vilaichone and Mahachai, 2001; Vilaichone et al., 2006). Furthermore, H. pylori eradication potentially reduces the incidence of gastric cancer, especially in high prevalence area of this particular cancer (Ford et al., 2014; Demirel et al., ...

Gastric cancers are sometimes diagnosed in patients who have successfully undergone Helicobacter pylori (H. pylori) eradication. We analyzed the clinicopathological features of gastric cancers detected after eradication to clarify their characteristics. We reviewed 31 patients with 34 cases of gastric cancer detected after successful H. pylori eradication. Clinicopathological characteristics an...

BACKGROUND/AIMS Trends in successful eradication of Helicobacter pylori using first-line triple therapy, consisting of a proton pump inhibitor, amoxicillin, and clarithromycin, have been understudied. We evaluated H. pylori eradication rates at a single center over the last 10 years and identified risk factors related to eradication failure. METHODS This study included 1,413 patients who were...

Our study included 59 children, aged 12.2 +/- 4.6 years, with Helicobacter pylori infection and 29 children, aged 11.0 +/- 4.2 years, with past H. pylori infection after spontaneous eradication with positive IgG antibodies against H. pylori and with functional disorders of the gastrointestinal tract, without H. pylori infection, with normal IgG concentration against H. pylori. All biopsy specim...

BACKGROUND Intestinal metaplasia is a precursor lesion of gastric cancer. Infection by Helicobacter pylori is the principal cause of metaplasia. While evidence of the regression of metaplasia after treatment to eradicate this infection has been demonstrated, controversy remains with regard to this subject. OBJECTIVE The objective of this study was to determine the frequency of the regression ...