testicular cancer is one of the commonest cancers in men of working age, and is increasing in incidence in europe and north america. one suggested mechanism of causation is that there is impaired differentiation of germ cells in the pre- or perinatal period, followed by malignant transformation in later life, possibly by a hormonal mechanism. endocrine disrupting chemicals (edcs) have been a ma...

Chronic diarrhea is a symptom which persists for ≥ 4 weeks as of disease. often becomes the patient’s cause to be referred gastroenterology. In general, prevalence chronic approximated 5% in each populations, but there are obstacles diagnosing diarrhea, due many differential diagnoses diarrhea. The could neoplasm and non-neoplasm. several studies, through results colonoscopy histopathology, it ...

Osteoblastoma is an unusual neoplasm, usually found in the vertebral column and long bones of extremities. Maxillary involvement extremely rare. We present a case report benign osteoblastoma maxilla affecting 17 year old young male patient. The clinical presentation, radiological histopathological features as well treatment modalities this neoplasm are briefly discussed. Lastly attempt made to ...

Hematologic malignancies often involve the pancreas, causing potential diagnostic pitfalls and, rarely, potentially avoidable surgical resection. We review the spectrum of hematologic malignancies involving the pancreas and describe features useful in preoperative distinction from adenocarcinoma. Archived clinical, pathologic, and radiologic data (1965 to present) for hematologic malignancies i...

BACKGROUND The JAK2 V617F mutation has been noted in the cases of polycythemia vera, essential thrombocythemia, and primary myelofibrosis patients. This mutation occurs less frequently in acute myeloid leukemia (AML) and other hematologic diseases, such as myelodysplastic syndrome (MDS); myelodysplatic syndrome/myeloproliferative neoplasm, unclassifiable (MDS/MPN-U); and refractory anemia with ...

Sweet’s syndrome, oral Malignancy Squamous-cell carcinoma A. Giménez-Arnau, MD, PhD, Department of Dermatology, Hospital del Mar, Passeig Maritim 25-29, E-08003 Barcelona (Spain) Sweet’s syndrome (SS) or acute febrile neutrophilic dermatosis [1] as marker of malignancy was suggested by Clemmensen et al. [2] in 1989. These patients show some of the severer cutaneous features of the disorder. The...

Metastasis into a thyroid neoplasm-tumor-to-tumor metastasis-is exceedingly rare. We describe the 28th documented case of a tumor metastatic to a thyroid neoplasm and review the literature on tumor-to-tumor metastasis involving a thyroid neoplasm as recipient. All cases showed a recipient thyroid neoplasm with an abrupt transition to a morphologically distinct neoplasm. Metastasis into primary ...

BACKGROUND Therapy-related myeloid neoplasms (t-MN) occur as late complications of cytotoxic therapy. This study reviewed clinical and cytogenetic characteristics of patients with t-MN at a single institution in Korea. METHODS The study subjects included 39 consecutive patients diagnosed with t-MN. Each subject's clinical history of previous diseases, treatments, and laboratory data was revie...