BACKGROUND Reactivation of HBV replication with an increase in serum HBV DNA and alanine aminotransferase (ALT) activity has been reported in 20-50% of hepatitis B carriers undergoing cytotoxic chemotherapy for cancer treatment. Manifestation of HBV reactivation ranges from asymptomatic self-limiting hepatitis to severe progressive hepatic failure and fatal consequences. AIM To investigate th...

Introduction The continuous and rapid growth of telecommunication industries, along with the common application of cell phones, hasraised debates on the associated risks for humanhealth due to exposure to radiofrequency fields, caused bycell phonesorother sources, and industrial and medical applications. Accordingly, in this study, we aimed to investigate the effects of cell phone radiation on ...

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the main curative therapy for hematological malignancy such as leukemias, lymphomas, or multiple myelomas and some other hematological disorders. In this therapy, cure of hematological diseases relies on graft-versus-malignancy effects by allogenic immune cells. However, severe posttransplant treatment-associated complications su...

The FOXP protein family (FOXP1-4) is a group of transcription factors that play important roles in embryological, immunological, hematological, and speech and language development. Here, we report FOXP1 de novo mutation and severe speech delay in an individual belonging to a non-Caucasian population.

background: metals such as iron, zinc, and copper are critical and necessary for the survival of all living organisms, whereas xenobiotic metals such as lead, cadmium, mercury, and arsenic have no known biologic role. any metals in high doses can have toxic effects. the aim of this work was to evaluate the hematological changes induced by lead as a toxic metal and characterize the potential eff...

splenic infarction occurs due to occlusion of splenic vessels that leads to splenic tissue ischemia and necrosis. there are several reports regarding splenic infarction in patients with acute myelogenous leukemia (aml). herein, we report a case of acute promyelocytic anemia (aml-m3) who presented with abdominal pain and splenic infarction.

sulfur mustard has been employed in chemical warfare in certain regions including iran. the short and long term biological effects of sulfur mustard contamination have been studied in both basic and clinical aspects. sulfur mustard has been shown to induce a vast array of pathological effects in affected persons. in addition to skin, lung, eyes and gastrointestinal disturbances, sulfur mustard ...

objectives: this study aimed to investigate the effect of water-pipe (wp) smoking on hematological parameters of wistar rats. methods: thirty-five young male rats (200-250 g) were randomly assigned to five groups (n=7). the control group was exposed to room air and the experimental groups were exposed to wp smoking, using a special apparatus designed to have the ability to keep the rats for 40 ...